在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UBA6 Antibody

UBA6 Antibody

  • 中文名稱：
    UBA6兔多克隆抗體
  • 貨號：
    CSB-PA025420LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA025420LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA025420LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA025420LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UBA6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    E1-L2 antibody; FLJ10808 antibody; FLJ23367 antibody; Monocyte protein 4 antibody; MOP 4 antibody; MOP-4 antibody; MOP4 antibody; UBA 6 antibody; Uba6 antibody; UBA6 ubiquitin activating enzyme E1 antibody; UBA6_HUMAN antibody; UBE1L2 antibody; Ubiquitin activating enzyme 6 antibody; Ubiquitin activating enzyme E1 like 2 antibody; Ubiquitin activating enzyme E1 like protein 2 antibody; Ubiquitin like modifier activating enzyme 6 antibody; Ubiquitin-activating enzyme 6 antibody; Ubiquitin-activating enzyme E1-like protein 2 antibody; Ubiquitin-like modifier-activating enzyme 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-like modifier-activating enzyme 6 protein (1-44AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，UBA6 Antibody (CSB-PA025420LA01HU)，的標記方式是Non-conjugated。對于UBA6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA025420LB01HU UBA6 Antibody, HRP conjugated ELISA
    FITC CSB-PA025420LC01HU UBA6 Antibody, FITC conjugated
    Biotin CSB-PA025420LD01HU UBA6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
  • 基因功能參考文獻：
    1. Polyubiquitination and proteasomal degradation of ezrin and CUGBP1 require Uba6, but not Uba1, and that Uba6 is involved in the control of ezrin localization and epithelial morphogenesis. These data suggest that distinctive substrate pools exist for Uba1 and Uba6 that reflect non-redundant biological roles for Uba6. PMID: 28134249
    2. this study revealed a novel function of LMO2 involving in the regulatory hierarchy of UBA6-USE1-FAT10ylation pathway by targeting the E1 enzyme UBA6. PMID: 27569286
    3. Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder. PMID: 26284580
    4. Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 and Uba6. PMID: 22999844
    5. Data indicate the potential role of cytokine-induced FAT10 expression in regulating Uba6 pathways. PMID: 22427669
    6. UBE1L2 is a novel E1 enzyme specific for ubiquitin PMID: 17580310
    7. Human Uba6 and Ube1 have distinct preferences for E2 charging in vitro, and their specificity depends in part on their C-terminal ubiquitin-fold domains, which recruit E2s PMID: 17597759
    8. The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10, is reported. PMID: 17889673
    9. Ubiquitin-like modifier activating enzyme 6 activates not only ubiquitin, but also the ubiquitin-like modifier FAT10[review] PMID: 18353650

    顯示更多

    收起更多

  • 蛋白家族：
    Ubiquitin-activating E1 family
  • 組織特異性：
    Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.
  • 數據庫鏈接：

    HGNC: 25581

    OMIM: 611361

    KEGG: hsa:55236

    STRING: 9606.ENSP00000313454

    UniGene: Hs.212774



主站蜘蛛池模板： 成在线人视频免费视频| 亚洲综合网站久久久| 中文在线www天堂网| 国产精品综合色区在线观看| 高潮添下面视频免费看| 99久久婷婷国产综合精品 | 小雪好紧好滑好湿好爽视频| 狼人亚洲国内精品自在线| 国产精品成人观看视频国产奇米 | 免费午夜爽爽爽www视频十八禁| 亚欧免费无码aⅴ在线观看蜜桃| 永久免费无码网站在线观看个| 他掀开裙子把舌头伸进去添视频| 777亚洲精品乱码久久久久久| 精品国产精品国产偷麻豆| 国产精品无码无卡无需播放器 | 国精产品999国精产| 曰本大码熟中文字幕| 久久久久人妻一区视色| 成人动漫综合网| 日本高清视频www| 无套内谢少妇毛片aaaa片免费| 精品露脸国产偷人在视频| 日本中文字幕在线| 学生妹亚洲一区二区| 国产成人综合色视频精品| 国产综合有码无码中文字幕| 中文字幕人乱码中文| 亚洲一区精品无码| 大学生久久香蕉国产线看观看| 亚洲腹肌男啪啪网站男同| 国产乱沈阳女人高潮乱叫老| 解开人妻的裙子猛烈进入| 亚洲熟妇av午夜无码不卡| 色屁屁www影院免费观看| 国产精品无码一区二区三区电影| 亚洲色大成网站www永久一区| 丁香五月激情综合亚洲| 夜夜夜夜猛噜噜噜噜噜| 一区二区视频| 午夜福利体验免费体验区|