在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. UBA6 Antibody

UBA6 Antibody

  • 中文名稱：
    UBA6兔多克隆抗體
  • 貨號：
    CSB-PA025420LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA025420LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA025420LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA025420LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UBA6 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    E1-L2 antibody; FLJ10808 antibody; FLJ23367 antibody; Monocyte protein 4 antibody; MOP 4 antibody; MOP-4 antibody; MOP4 antibody; UBA 6 antibody; Uba6 antibody; UBA6 ubiquitin activating enzyme E1 antibody; UBA6_HUMAN antibody; UBE1L2 antibody; Ubiquitin activating enzyme 6 antibody; Ubiquitin activating enzyme E1 like 2 antibody; Ubiquitin activating enzyme E1 like protein 2 antibody; Ubiquitin like modifier activating enzyme 6 antibody; Ubiquitin-activating enzyme 6 antibody; Ubiquitin-activating enzyme E1-like protein 2 antibody; Ubiquitin-like modifier-activating enzyme 6 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Ubiquitin-like modifier-activating enzyme 6 protein (1-44AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，UBA6 Antibody (CSB-PA025420LA01HU)，的標記方式是Non-conjugated。對于UBA6 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA025420LB01HU UBA6 Antibody, HRP conjugated ELISA
    FITC CSB-PA025420LC01HU UBA6 Antibody, FITC conjugated
    Biotin CSB-PA025420LD01HU UBA6 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
  • 基因功能參考文獻：
    1. Polyubiquitination and proteasomal degradation of ezrin and CUGBP1 require Uba6, but not Uba1, and that Uba6 is involved in the control of ezrin localization and epithelial morphogenesis. These data suggest that distinctive substrate pools exist for Uba1 and Uba6 that reflect non-redundant biological roles for Uba6. PMID: 28134249
    2. this study revealed a novel function of LMO2 involving in the regulatory hierarchy of UBA6-USE1-FAT10ylation pathway by targeting the E1 enzyme UBA6. PMID: 27569286
    3. Interstitial microdeletions including the chromosome band 4q13.2 and the UBA6 gene as possible causes of intellectual disability and behavior disorder. PMID: 26284580
    4. Diminished ubiquitylation phenotype observed in enteropathogenic Escherichia coli infected cells corresponds to a strong reduction in the abundance of both Ube1 and Uba6. PMID: 22999844
    5. Data indicate the potential role of cytokine-induced FAT10 expression in regulating Uba6 pathways. PMID: 22427669
    6. UBE1L2 is a novel E1 enzyme specific for ubiquitin PMID: 17580310
    7. Human Uba6 and Ube1 have distinct preferences for E2 charging in vitro, and their specificity depends in part on their C-terminal ubiquitin-fold domains, which recruit E2s PMID: 17597759
    8. The identification of an E1-like protein, termed E1-L2, that activates both ubiquitin and another ubiquitin-like protein, FAT10, is reported. PMID: 17889673
    9. Ubiquitin-like modifier activating enzyme 6 activates not only ubiquitin, but also the ubiquitin-like modifier FAT10[review] PMID: 18353650

    顯示更多

    收起更多

  • 蛋白家族：
    Ubiquitin-activating E1 family
  • 組織特異性：
    Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.
  • 數據庫鏈接：

    HGNC: 25581

    OMIM: 611361

    KEGG: hsa:55236

    STRING: 9606.ENSP00000313454

    UniGene: Hs.212774



主站蜘蛛池模板： 最近免费中文字幕mv在线视频3| 国产男女猛烈视频在线观看| 中文字幕人妻被公上司喝醉506| 国产成人精品一区二区三区无码| 国产亚洲精品a在线无码| 无码专区—va亚洲v专区vr| av天堂久久精品影音先锋| 老司机午夜福利av无码特黄a| 国产成人av无码精品| 久久精品人人槡人妻人| 疯狂迎合进入强壮公的视频| 精品人妻二区中文字幕| 老熟妇高潮一区二区三区| 97国产精品麻豆性色aⅴ人妻波| 蜜芽av无码精品国产午夜| 真正免费毛片在线播放| 亚洲第一区无码专区| 狠狠色噜噜狠狠狠狠888奇禾 | 做性久久久久久| 日本一区二区三区免费播放| 免费精品国产人妻国语| 成在人线av无码免观看| 青楼妓女禁脔道具调教sm| 国产精品免费视频网站| 精品亚洲一区二区三区四区五区 | 欧美成人看片一区二区三区尤物| 国产69精品久久久久久妇女迅雷| 国产午夜鲁丝片av无码免费| 国产亚洲婷婷香蕉久久精品| 人人妻人人澡人人爽国产一区| 亚洲国产欧美不卡在线观看| 国模雨珍浓密毛大尺度150p| 亚洲日韩乱码一区二区三区四区| 国产有奶水哺乳期无码avav| 中国熟妇内谢69xxxxx| 色噜噜狠狠狠狠色综合久一| 亚洲无人区码一码二码三码的含义| 亚洲精品国产美女久久久| 欧洲熟妇色xxxx欧美老妇软件| 免费超爽大片黄| 日日橹狠狠爱欧美视频|