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  4. TXNRD3 Antibody

TXNRD3 Antibody

  • 中文名稱：
    TXNRD3兔多克隆抗體
  • 貨號：
    CSB-PA025390GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TXNRD3
  • 別名：
    TGR antibody; Thioredoxin and glutathione reductase antibody; Thioredoxin glutathione reductase antibody; Thioredoxin reductase 2 antibody; Thioredoxin reductase 3 antibody; Thioredoxin reductase TR2 antibody; TR2 antibody; TRXR3 antibody; TRXR3_HUMAN antibody; TXNRD3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Human TXNRD3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
  • 基因功能參考文獻：
    1. Findings represent the first characterization of hTGR and provide new insights into the reaction mechanism and the regulation of monothiol Grx-containing thioredoxin glutathione reductases. PMID: 29222842
    2. A role of GPx2, TrxR2 and TrxR3 in proliferation, apoptosis and, therefore, also during cancer development. PMID: 22683372
    3. This study pertains to use of non-AUG (CUG) start codon in mouse thioredoxin reductase 3 gene, and conservation of this site in other mammals. PMID: 20018845
  • 亞細胞定位：
    Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum.
  • 蛋白家族：
    Class-I pyridine nucleotide-disulfide oxidoreductase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20667

    OMIM: 606235

    KEGG: hsa:114112

    STRING: 9606.ENSP00000430031

    UniGene: Hs.477475



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