TXNRD3 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q86VQ6
基因名：

TXNRD3
別名：

TGR antibody; Thioredoxin and glutathione reductase antibody; Thioredoxin glutathione reductase antibody; Thioredoxin reductase 2 antibody; Thioredoxin reductase 3 antibody; Thioredoxin reductase TR2 antibody; TR2 antibody; TRXR3 antibody; TRXR3_HUMAN antibody; TXNRD3 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Human TXNRD3
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
基因功能參考文獻：
1. Findings represent the first characterization of hTGR and provide new insights into the reaction mechanism and the regulation of monothiol Grx-containing thioredoxin glutathione reductases. PMID: 29222842
2. A role of GPx2, TrxR2 and TrxR3 in proliferation, apoptosis and, therefore, also during cancer development. PMID: 22683372
3. This study pertains to use of non-AUG (CUG) start codon in mouse thioredoxin reductase 3 gene, and conservation of this site in other mammals. PMID: 20018845
亞細胞定位：

Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum.
蛋白家族：

Class-I pyridine nucleotide-disulfide oxidoreductase family
數(shù)據(jù)庫鏈接：

HGNC: 20667

OMIM: 606235

KEGG: hsa:114112

STRING: 9606.ENSP00000430031

UniGene: Hs.477475

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