在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TXNDC5 Antibody

TXNDC5 Antibody

  • 中文名稱：
    TXNDC5兔多克隆抗體
  • 貨號：
    CSB-PA847679ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: TXNDC5 antibody at 4.9μg/ml
      Lane 1: HepG2 whole cell lysate
      Lane 2: Colo320 whole cell lysate
      Lane 3: Mouse stomach tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 48, 37 kDa
      Observed band size: 48 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA847679ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA847679ESR1HU at dilution of 1:100
    • Immunoprecipitating TXNDC5 in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA847679ESR1HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA847679ESR1HU (8μg) + HepG2 whole cell lysate (500μg)
      Lane 3: HepG2 whole cell lysate (10μg)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TXNDC5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EndoPDI antibody; Endoplasmic reticulum protein ERp46 antibody; Endoplasmic reticulum resident protein 46 antibody; Endothelial protein disulphide isomerase antibody; ER protein 46 antibody; ERp46 antibody; Hcc 2 antibody; MGC3178 antibody; PDIA15 antibody; Protein disulfide isomerase family A member 15 antibody; STRF8 antibody; Thioredoxin domain containing 5 (endoplasmic reticulum) antibody; Thioredoxin domain containing 5 antibody; Thioredoxin domain containing protein 5 antibody; Thioredoxin domain-containing protein 5 antibody; Thioredoxin like protein p46 antibody; Thioredoxin related protein antibody; Thioredoxin-like protein p46 antibody; TLP46 antibody; TXND5_HUMAN antibody; TXNDC 5 antibody; Txndc5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Thioredoxin domain-containing protein 5 protein (1-324AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast.
  • 基因功能參考文獻：
    1. Hypoxia induces the expression of TXNDC5 via upregulating HIF-1alpha in colorectal cancer cells. PMID: 29749460
    2. TXNDC5 is also closely associated with rheumatoid arthritis, diabetes, hepatic steatosis and vitiligo. [review] PMID: 28604976
    3. High TXNDC5 expression is associated with renal cell carcinoma. PMID: 26810069
    4. we defined an important role of TXNDC5 in CRPC and further investigations are needed to screen TXNDC5 antagonists as a novel therapeutic approaches to treat PCa patients with Castration-resistant prostate cancer. PMID: 25500540
    5. Role of ERp46 in oxidative protein folding.Independent actions of ERp46 thioredoxin domains on folding substrates.Structure of thioredoxin ERp46 domains. PMID: 24462249
    6. suggest that the tumorigenic properties of ERp46 in RCC cells are not related to an inhibitory modulation of AdipoR1 PMID: 24594673
    7. Endo-PDI is a novel, important mediator of AP-1-driven gene expression and endothelial angiogenic function. PMID: 24103565
    8. TXNDC5 has increased expression in many tumors that is involved in the proliferation and migration of tumor cells, acting as a tumor-enhancing gene. PMID: 24100949
    9. results suggest that TXNDC5 polymorphisms could be related to the development of HCC in the Korean male population PMID: 24023338
    10. Hyperoxidized peroxiredoxin 2 interacts with the protein disulfide- isomerase ERp46. PMID: 23713588
    11. Hypoxia induced TXCNDC5 expression, which contributed to adiponectin expression, cytokine production and the cellular proliferation and migration of fibroblasts in rheumatoid arthritis. PMID: 23326410
    12. Authors show that ERp46 is able to bind to a large pool of peptides containing aromatic and basic residues via all three of its catalytic domains (a(0), a and a'), though the a(0) domain may contain the primary binding site. PMID: 23376096
    13. crystal structure of the third catalytic domain of protein disulfide isomerase ERp46 (also known as protein disulfide isomerase A5 and TXNDC5) was determined to 2.0 A resolution PMID: 22505402
    14. TXNDC5 has a genetic effect on the risk of rheumatoid arthritis and ankylosing spondylitis PMID: 21801346
    15. Overexpression of the TXNDC5 protein is associated with non-small cell lung carcinoma. PMID: 21617212
    16. results suggest that TXNDC5 gene polymorphisms are associated with the development of nonsegmental vitiligo in the Korean population. PMID: 19906073
    17. TXNDC5 can promote the growth and proliferation of gastric cells. Silencing of TXNDC5 can restrain the growth and proliferation of gastric cancer cells. PMID: 20157732
    18. these results establish ERp46 as the first AdipoR1-specific interacting protein and suggest a role for ERp46 in adiponectin receptor biology and adiponectin signalling. PMID: 20074551
    19. ERp46 has specificity towards peroxiredoxin-4, a thioredoxin peroxidase. PMID: 19887585
    20. upregulation of TXNDC5 are involved in the early development of colorectal cancer PMID: 17895523
    21. Member of the protein disulphide isomerase family and highly expressed in endothelial cells. Protects endothelial cells from apoptosis under hypoxia. PMID: 12963716

    顯示更多

    收起更多

  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Protein disulfide isomerase family
  • 數據庫鏈接：

    HGNC: 21073

    OMIM: 616412

    KEGG: hsa:81567

    STRING: 9606.ENSP00000369081

    UniGene: Hs.150837



主站蜘蛛池模板： 人妻熟女一区二区aⅴ千叶宁真 | 亚洲日韩一区二区| 国产精品露脸国语对白| 天堂mv在线mv免费mv香蕉| 免费无码一区二区三区a片| 久久精品国产久精国产果冻传媒| 亚洲国产欧美在线成人app| 天堂无码人妻精品av一区| 国产精品亚洲lv粉色| 国产亚洲精品久久久久久小舞| 亚洲乱码日产精品bd在线| 在线天堂最新版资源| 久久久久国产精品嫩草影院| 国产伦子沙发午休系列资源曝光| 亚洲成av人片天堂网久久| 亚洲欧美日韩国产国产a| 亚洲精品永久在线观看| 国产国语毛片在线看国产| 丰满少妇aaaaaa爰片毛片| 亚洲日本在线电影| 97se亚洲国产综合自在线观看| 亚洲日韩性欧美中文字幕| 亚洲天天做日日做天天欢毛片| 99热这里只有精品免费播放| 边吃奶边添下面好爽| 亚洲精品无码乱码成人| 亚洲国产精品va在线看黑人 | 又粗又硬又黄又爽的视频永久| 亚洲精品一区二区三区中文字幕 | 亚洲五月天综合| 亚洲国产综合精品 在线 一区| 在线看片免费人成视频影院看| 狠狠色色综合网站| 国产色在线 | 亚洲| 2020年最新国产精品正在播放| 国产精品青草久久福利不卡| 女人被男人爽到呻吟的视频| 九九影院午夜理论片少妇| 高潮潮喷奶水飞溅视频无码 | 国产免费无码一区二区视频| 久久国产免费观看精品3|