在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TTC8 Antibody

TTC8 Antibody

  • 中文名稱：
    TTC8兔多克隆抗體
  • 貨號：
    CSB-PA025244GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TTC8
  • 別名：
    Bardet Biedl syndrome 8 protein antibody; Bardet Biedl syndrome type 8 antibody; Bardet-Biedl syndrome 8 protein antibody; BBS8 antibody; RP51 antibody; Tetratricopeptide repeat domain 8 antibody; Tetratricopeptide repeat protein 8 antibody; TPR repeat protein 8 antibody; TTC 8 antibody; Ttc8 antibody; TTC8_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TTC8
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
  • 基因功能參考文獻：
    1. A splice-site mutation in a retina-specific exon of TTC8 causes nonsyndromic retinitis pigmentosa. PMID: 20451172
    2. A homozygous null BBS8 mutation leads to Bardet-Biedl syndrome with randomization of left-right body axis symmetry, a known defect of the nodal cilium PMID: 14520415
  • 相關疾病：
    Retinitis pigmentosa 51 (RP51); Bardet-Biedl syndrome 8 (BBS8)
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cell projection, cilium.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 20087

    OMIM: 608132

    KEGG: hsa:123016

    STRING: 9606.ENSP00000370031

    UniGene: Hs.303055



主站蜘蛛池模板： 国产午夜精华2020在线| 玩两个丰满老熟女| 国产激情艳情在线看视频 | 亚洲男女一区二区三区| 呦系列视频一区二区三区| 成人看片黄a免费看在线| 亲子乱av一区二区三区| 999成人精品视频在线| 成人国产一区二区精品小说| 欧美性潮喷xxxxx免费视频看| 亚洲五月天综合| 国产精品vr专区| 久久综合给合久久狠狠狠88| 人妻性奴波多野结衣无码| 欧美多毛肥胖老妇做爰| 欧美丰满熟妇hdxx| 亚洲国产99精品国自产拍| 国产制服丝袜欧美在线观看| 亚洲精品一区国产精品| 国产真实乱人偷精品视频| 国产免费又色又爽又黄软件| 亚欧日韩欧美网站在线看 | 无码人妻少妇伦在线电影| 欧美巨大黑人极品精男| 99久久无码一区人妻a黑| 伊人99综合精品视频| 国产网红无码精品视频| 天堂中文在线资源| 天天狠天天透天干天天| 国产精品亚洲专区无码破解版| 精品久久久久久| 国产精品人人妻人人爽| 老司机午夜精品视频资源| 精品人妻无码一区二区三区蜜桃一| 国产精品自产拍高潮在线观看 | 香蕉成人伊视频在线观看| 亚洲国产精品一区二区动图 | 四虎精品成人a在线观看| 99精品免费久久久久久久久日本 | 高潮毛片无遮挡高清免费| 日本特黄特黄刺激大片|