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  4. TTC12 Antibody, Biotin conjugated

TTC12 Antibody, Biotin conjugated

  • 中文名稱：
    TTC12兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA862040LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TTC12 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TTC12
  • 別名：
    TTC12 antibody; Tetratricopeptide repeat protein 12 antibody; TPR repeat protein 12 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Tetratricopeptide repeat protein 12 protein (1-260AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cytoplasmic protein that plays a role in the proper assembly of dynein arm complexes in motile cilia in both respiratory cells and sperm flagella.
  • 基因功能參考文獻：
    1. TTC12 SNP rs7130431 was associated with heroin dependence. PMID: 23303482
    2. TTC12-ANKK1-DRD2s seemed to influence smoking behavior mainly in adolescence, and its effect is partially mediated by personality characteristics promoting drug-seeking behavior. PMID: 21168125
    3. This study evaluated the interaction of ANKK1, TTC12, sex, and continental ancestry in tobacco smokers. PMID: 20133381
    4. the TTC12 gene is hypermethylated in acute lymphoblastic leukemia PMID: 17657212
    5. association studies of alcohol dependence and 43 SNPs mapped to the gene cluster of NCAM1, TTC12, ANKK1 and DRD2 PMID: 17761687
    6. Genetic linkage tests conclude that variants in TTC12 exon 3 are involved in the regulation of risk for comorbid alcohol and drug dependence. PMID: 18828801

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  • 亞細胞定位：
    Cytoplasm.
  • 組織特異性：
    Expressed in testis and in epithelial cells of trachea and bronchial tube.
  • 數據庫鏈接：

    HGNC: 23700

    OMIM: 610732

    KEGG: hsa:54970

    STRING: 9606.ENSP00000433757

    UniGene: Hs.288772



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