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  4. TSSK4 Antibody

TSSK4 Antibody

  • 中文名稱：
    TSSK4兔多克隆抗體
  • 貨號：
    CSB-PA004341
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HT29 cells using TSSK 4 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TSSK4
  • 別名：
    C14orf20 antibody; Serine/threonine-protein kinase 22E antibody; STK22E antibody; Testis-specific kinase 4 antibody; Testis-specific serine/threonine-protein kinase 4 antibody; TSK-4 antibody; TSSK-4 antibody; Tssk4 antibody; TSSK4_HUMAN antibody; TSSK5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human TSSK 4.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Serine/threonine kinase which is involved in male germ cell development and in mature sperm function. May be involved in the Cre/Creb signaling pathway. Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells. Phosphorylates CREM on 'Ser-116' in vitro. Phosphorylates ODF2 on 'Ser-95'.
  • 基因功能參考文獻：
    1. TSSK4 was able to induce cell apoptosis in vitro depending on its kinase activity, which leads to abnormal testes weight and apoptosis, shedding light on its function in the process of spermatogenesis and/or spermiogenesis PMID: 25877358
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
    3. association of some single nucleotide polymorphisms in TSSK4 with male infertility. PMID: 18390560
    4. Observational study of gene-disease association. (HuGE Navigator) PMID: 18390560
  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family
  • 組織特異性：
    Expressed only in the testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 19825

    OMIM: 610711

    KEGG: hsa:283629

    STRING: 9606.ENSP00000339179

    UniGene: Hs.314432



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