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  4. TSGA10 Antibody, Biotin conjugated

TSGA10 Antibody, Biotin conjugated

  • 中文名稱：
    TSGA10兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA863172LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TSGA10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TSGA10
  • 別名：
    Cancer/testis antigen 79 antibody; CEP4L antibody; CT79 antibody; Predicted testis protein antibody; Testis development protein NYD-SP7 antibody; Testis-specific gene 10 protein antibody; Testis-specific protein 10 antibody; TSG10_HUMAN antibody; Tsga10 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Testis-specific gene 10 protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A.
  • 基因功能參考文獻：
    1. TSGA10 tends to express variants with shorter 5'UTR. PMID: 28739310
    2. Overexpression of TSGA10 would induce disruption of HIF-1alpha axis and exert potent inhibitory effects on tumor angiogenesis and metastasis. PMID: 26573430
    3. Report role for mir-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression. PMID: 24294352
    4. TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients PMID: 21198756
    5. TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin PMID: 20797700
    6. over-expressed in 4 of 20 hepatocellular carcinomas (HCC), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers PMID: 15107545
    7. The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia. PMID: 16406020
    8. TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1). PMID: 18000009

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  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
  • 蛋白家族：
    CEP135/TSGA10 family
  • 組織特異性：
    Expressed in the testis, in spermatozoa (at protein level). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach.
  • 數據庫鏈接：

    HGNC: 14927

    OMIM: 607166

    KEGG: hsa:80705

    STRING: 9606.ENSP00000347161

    UniGene: Hs.120267



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