在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TSEN54 Antibody

TSEN54 Antibody

  • 中文名稱：
    TSEN54兔多克隆抗體
  • 貨號：
    CSB-PA272793
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from 3T3 cells and Jurkat cells, using TSEN54 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TSEN54 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TSEN54 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TSEN54
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human TSEN54.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • 基因功能參考文獻：
    1. TSEN54 gene-related pontocerebellar hypoplasia type 2 presented with exaggerated startle response in cousins. PMID: 26701950
    2. A novel heterozygous mutation was found in the TSEN54 gene by c.254A > T(+) (p.E85V), which may be a new subtype of hereditary ataxia PMID: 24938831
    3. TSEN54 mutation causes a severe form of pontocerebellar hypoplasia type 1 in a family. PMID: 21468723
    4. The results demonistrated that not all cases of clinically defined pontocerebellar hypoplasia-4 result from mutations in TSEN54. PMID: 21383226
    5. We confirm that the common p.A307S mutation in TSEN54 is responsible for most of the patients with a PCH2 phenotype. PMID: 20956791
    6. In two subtypes, PCH2 and PCH4, we identified mutations in three of the four different subunits of the tRNA-splicing endonuclease complex. PMID: 18711368

    顯示更多

    收起更多

  • 相關疾病：
    Pontocerebellar hypoplasia 4 (PCH4); Pontocerebellar hypoplasia 2A (PCH2A); Pontocerebellar hypoplasia 5 (PCH5)
  • 亞細胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    SEN54 family
  • 數據庫鏈接：

    HGNC: 27561

    OMIM: 225753

    KEGG: hsa:283989

    STRING: 9606.ENSP00000327487

    UniGene: Hs.378501



主站蜘蛛池模板： 亚洲欧洲av综合色无码| 国产色爱av资源综合区| 天堂www中文在线资源| 性按摩xxxx在线观看| 久久精品农村毛片| 免费国产成人午夜福利电影| 白丝爆浆18禁一区二区三区| 少妇仑乱a毛片| 日韩精品极品视频在线观看免费 | 欧美精品乱码99久久蜜桃| 久久青青草原国产免费播放| 免费无码av片在线观看| 欧美性性性性o00xx| 亚洲国产成人久久一区| 熟妇人妻中文字幕无码老熟妇| 亚洲熟妇色自偷自拍另类| 国产亚洲综合区成人国产| 无人区一线二线三线乱码| 国产精品成人免费视频网站京东| www国产精品内射熟女| 老牛精品亚洲成av人片| 亚洲精品宾馆在线精品酒店| 嫩草国产露脸精品国产软件| 顶级欧美熟妇xx| 成 人 在 线 免费观看 | 中文字幕无码av免费久久| 日本猛少妇色xxxxx猛叫| 久久久久久久久久久国产 | 正在播放国产真实哭都没用| 亚洲色偷偷偷网站色偷一区| 亚洲精品av无码喷奶水网站| 成人国产片女人爽到高潮| 人妻丰满熟妇无码区免费| 国产人妻久久精品二区三区| 精品国产va久久久久久久冰| 久久久久无码国产精品不卡| 亚洲国产av玩弄放荡人妇| 精品多人p群无码| 国产成人亚洲综合| 亚洲乱亚洲乱妇无码| 国产360激情盗摄全集|