在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TSEN54 Antibody

TSEN54 Antibody

  • 中文名稱：
    TSEN54兔多克隆抗體
  • 貨號：
    CSB-PA272793
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from 3T3 cells and Jurkat cells, using TSEN54 antibody.
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using TSEN54 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TSEN54 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TSEN54
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human TSEN54.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
  • 基因功能參考文獻：
    1. TSEN54 gene-related pontocerebellar hypoplasia type 2 presented with exaggerated startle response in cousins. PMID: 26701950
    2. A novel heterozygous mutation was found in the TSEN54 gene by c.254A > T(+) (p.E85V), which may be a new subtype of hereditary ataxia PMID: 24938831
    3. TSEN54 mutation causes a severe form of pontocerebellar hypoplasia type 1 in a family. PMID: 21468723
    4. The results demonistrated that not all cases of clinically defined pontocerebellar hypoplasia-4 result from mutations in TSEN54. PMID: 21383226
    5. We confirm that the common p.A307S mutation in TSEN54 is responsible for most of the patients with a PCH2 phenotype. PMID: 20956791
    6. In two subtypes, PCH2 and PCH4, we identified mutations in three of the four different subunits of the tRNA-splicing endonuclease complex. PMID: 18711368

    顯示更多

    收起更多

  • 相關疾病：
    Pontocerebellar hypoplasia 4 (PCH4); Pontocerebellar hypoplasia 2A (PCH2A); Pontocerebellar hypoplasia 5 (PCH5)
  • 亞細胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    SEN54 family
  • 數據庫鏈接：

    HGNC: 27561

    OMIM: 225753

    KEGG: hsa:283989

    STRING: 9606.ENSP00000327487

    UniGene: Hs.378501



主站蜘蛛池模板： 日韩精品av一区二区三区| 女女互磨互喷水高潮les呻吟| 夜爽8888视频在线观看| 呻吟国产av久久一区二区| 成人无遮挡18禁免费视频| 夫妻免费无码v看片| 成人性生交大片免费看r链接| 亚洲中文字幕无码人在线| 无码人妻少妇久久中文字幕蜜桃| 国产无人区码一码二码三mba| 欧美成人看片一区二区三区尤物| 中文无码字幕中文有码字幕| 人妻性奴波多野结衣无码| 国产人碰人摸人爱免费视频| 特黄特色的大片观看免费视频| 日韩av片无码一区二区三区| 在线观看成人无码中文av天堂不卡| 国产午夜亚洲精品国产成人小说| 精品无码一区二区三区不卡| 亚洲欧美日本中文字不卡| 99久久er热在这里只有精品99| 日本无码欧美一区精品久久| 欧美成人va免费大片视频| 久久大香线蕉国产精品免费| 美女内射毛片在线看3d| 色翁荡息又大又硬又粗又爽电影| 国产精品_国产精品_k频道| 人妻av无码中文专区久久| 久久午夜夜伦鲁鲁片免费无码| 久久精品成人无码观看不卡| 国产亚洲精品久久久久久彩霞| 国产大片黄在线观看| 亚洲综合在线另类色区奇米| 亚洲日本中文字幕乱码在线| 四虎av永久在线精品免费观看 | 午夜一区二区亚洲福利| 业余 自由 性别 成熟偷窥| 久久精品成人免费国产| 熟妇人妻不卡中文字幕| 精品香蕉一区二区三区| 国产精品亚洲w码日韩中文|