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  4. TRNAU1AP Antibody, HRP conjugated

TRNAU1AP Antibody, HRP conjugated

  • 中文名稱：
    TRNAU1AP兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA882127LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TRNAU1AP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRNAU1AP
  • 別名：
    1110007F05Rik antibody; AA387999 antibody; FLJ20503 antibody; PRO1902 antibody; RP4 669K10.4 antibody; SECp43 antibody; tRNA selenocysteine 1-associated protein 1 antibody; tRNA selenocysteine associated protein 1 antibody; tRNA selenocysteine-associated protein 1 antibody; Trnau1ap antibody; TRSPAP1 antibody; TSAP1_HUMAN antibody; WI1 2643G14.2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human tRNA selenocysteine 1-associated protein 1 protein (33-156AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
  • 基因功能參考文獻：
    1. Knockdown of Trnau1ap reduced cell migration and proliferation. Knockdown of Trnau1ap blocked the PI3K/Akt signaling pathway. PMID: 29758194
    2. Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. PMID: 28414460
    3. our studies delineating the multiple, coordinated protein-nucleic acid interactions between SECp43 and the selenoprotein cotranslational factors. PMID: 16508009
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    RRM TRSPAP family
  • 數據庫鏈接：

    HGNC: 30813

    KEGG: hsa:54952

    STRING: 9606.ENSP00000362936

    UniGene: Hs.533626



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