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  4. TRMT112 Antibody, FITC conjugated

TRMT112 Antibody, FITC conjugated

  • 中文名稱：
    TRMT112兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA883416LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TRMT112 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRMT112
  • 別名：
    TRMT112 antibody; AD-001 antibody; HSPC152 antibody; HSPC170 antibody; Multifunctional methyltransferase subunit TRM112-like protein antibody; tRNA methyltransferase 112 homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with HEMK2/N6AMT1 also monomethylates 'Lys-12' of histone H4 (H4K12me1). The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA.
  • 基因功能參考文獻：
    1. The localization of the TRMT112 protein is determined by WBSCR22, and the WBSCR22-TRMT112 complex is localized in the cell nucleus. PMID: 26214185
  • 亞細胞定位：
    Nucleus, nucleoplasm. Cytoplasm, perinuclear region.
  • 蛋白家族：
    TRM112 family
  • 數據庫鏈接：

    HGNC: 26940

    KEGG: hsa:51504

    STRING: 9606.ENSP00000438349

    UniGene: Hs.333579



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