在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIP10 Antibody

TRIP10 Antibody

  • 中文名稱：
    TRIP10兔多克隆抗體
  • 貨號：
    CSB-PA624029LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA624029LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA624029LA01HU at dilution of 1:100
    • Immunofluorescent analysis of PC-3 cells using CSB-PA624029LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRIP10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Cdc42 interacting protein 4 antibody; Cdc42 interaction protein 4 long isoform antibody; Cdc42-interacting protein 4 antibody; CG11341 antibody; CG15015 PA antibody; Cip 4 antibody; CIP4 antibody; CIP4_HUMAN antibody; DCIP4 antibody; hSTP antibody; Protein Felic antibody; Salt tolerant protein antibody; Salt tolerator antibody; STOT antibody; STP antibody; Thyroid hormone receptor interactor 10 antibody; Thyroid receptor interacting protein 10 antibody; Thyroid receptor-interacting protein 10 antibody; TR-interacting protein 10 antibody; TRIP 10 antibody; TRIP-10 antibody; trip10 antibody; Truncated Cdc42 interaction protein 4 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Cdc42-interacting protein 4 protein (276-486AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TRIP10 Antibody (CSB-PA624029LA01HU)，的標記方式是Non-conjugated。對于TRIP10 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應用
    HRP CSB-PA624029LB01HU TRIP10 Antibody, HRP conjugated ELISA
    FITC CSB-PA624029LC01HU TRIP10 Antibody, FITC conjugated
    Biotin CSB-PA624029LD01HU TRIP10 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
  • 基因功能參考文獻：
    1. Data show that CIP4 is highly expressed in nasopharyngeal carcinoma (NPC) tissues and is associated with poor prognosis. Also, the study provides evidence that CIP4 plays an important role in the promotion of NPC metastasis by mediating invadopodia formation and activating the EGFR pathway. PMID: 28129778
    2. results support a model in which AKAP350 recruits CIP4 to the centrosome, providing a centrosomal scaffold to integrate microtubule and actin dynamics, thus enabling centrosome polarization and ensuring cell migration directionality. PMID: 26208639
    3. CIP4 promotes metastasis in Triple negative breast cancer and is associated with poor prognosis. PMID: 25823823
    4. CIP4 is a positive regulator of non small lung carcinoma metastasis and a potential poor prognostic biomarker in lung adenocarcinoma. PMID: 25174397
    5. CIP4 controls cell-cell cohesion and is required for the acquisition of an invasive phenotype in breast tumors PMID: 25203208
    6. CIP4 plays a significant role in the intracellular hypertrophic signal transduction network that controls the growth of cardiac myocytes in heart disease. PMID: 23915320
    7. Study reveals a critical role of CIP4 in mediating chemotaxis of CLL cells by controlling the dynamics of microspike-containing protrusions and cell steering. PMID: 23644527
    8. Trip10 regulates cancer cell growth and death in a cancer type-specific manner. Differential DNA methylation of Trip10 can either promote cell survival or cell death in a cell type-dependent manner. PMID: 21299869
    9. CIP4 overexpression is associated with breast cancer. PMID: 20940394
    10. Identification and genetic analysis of human and mouse activated Cdc42 interacting protein-4 isoforms PMID: 12054674
    11. CIP4 accumulation and cellular toxicity may have a role in Huntington's disease pathogenesis PMID: 12604778
    12. These results indicate that CIP4 is critical for beta-catenin-mediated cell-cell adhesion. PMID: 16343437
    13. Data showed the SH3 domain of CIP4 was bound to DAAM1 in vivo. PMID: 16630611
    14. CIP4 is an important cytoskeletal adaptor that functions after filamentous actin accumulation and Cdc42 activation to enable microtubule organizing center polarization and NK cell cytotoxicity PMID: 17785506
    15. Cdc42-Interacting Protein-4 and FNBP1L protein potentially regulate later events in Epidermal Growth Factor Receptor endocytic trafficking that limits compartmentalized EGFR signaling. PMID: 19632321
    16. FNBP1 family proteins (FNBP1 and TRIP10) consist of FCH, FBH and SH3 domains. PMID: 12736724

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup.; [Isoform 5]: Cytoplasm, perinuclear region.
  • 蛋白家族：
    FNBP1 family
  • 組織特異性：
    Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 12304

    OMIM: 604504

    KEGG: hsa:9322

    UniGene: Hs.515094



主站蜘蛛池模板： 菠萝蜜视频在线观看入口| 欧美老妇乱辈通奷| 国产欧美日韩亚洲18禁在线| 国产大学生粉嫩无套流白浆| 亚洲老妈激情一区二区三区| 国产成人精品123区免费视频| 成人网站免费观看| 国语自产免费精品视频在| 国产 制服丝袜 动漫在线| 精品蜜臀久久久久99网站 | 国产精品sp调教打屁股| 免费无码久久成人影片| 色欲天天天天天综合网| 狠狠色丁香久久综合| 国产精品久久国产三级国不卡顿 | 精品国产综合成人亚洲区| 中日韩精品无码一区二区三区| 最新国产精品无码| 国产人妻大战黑人20p| 欧美最猛性xxxxx免费| 亚洲国产精品成人精品无码区在线| 成人午夜福利院在线观看| 国产无遮挡a片无码免费软件| 国产涩涩视频在线观看| 精品人体无码一区二区三区| 久久久www成人免费看片| 狠狠做五月深爱婷婷| 国产成人无码www免费视频播放| 久久国产avjust麻豆| 麻豆熟妇人妻xxxxxx| 伊人色综合一区二区三区影院视频 | 邻居少妇张开双腿让我爽一夜| 国产精品无码a∨精品影院app| 亚洲精品av一二三区无码| 国产成人一区二区三区app| 国产午夜片无码区在线播放| 国产偷人妻精品一区| 久久亚洲道色综合久久| 亚洲六月丁香六月婷婷| 国产精品亚洲欧美大片在线看| 综合图区亚洲另类偷窥|