在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM71 Antibody

TRIM71 Antibody

  • 中文名稱：
    TRIM71兔多克隆抗體
  • 貨號：
    CSB-PA173135
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA173135(TRIM71 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM71
  • 別名：
    2610206G21Rik antibody; Abnormal cell LINeage LIN 41 antibody; AL022943 antibody; E3 ubiquitin-protein ligase TRIM71 antibody; Gm1127 antibody; Homolog of C. elegans Lin 41 antibody; LIN 41 antibody; LIN41 antibody; LIN41_HUMAN antibody; mlin 41 antibody; Protein lin 41 homolog antibody; Protein lin-41 homolog antibody; RGD1566388 antibody; Ripply2 antibody; TRIM 71 antibody; TRIM71 antibody; Tripartite motif containing 71 antibody; Tripartite motif-containing protein 71 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human TRIM71
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1. Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression.
  • 基因功能參考文獻：
    1. TRIM71 acts through post-transcriptional repression of Lin28B and subsequent modulation of let-7-HMGA2 signaling during tumorigenesis to potentially function as a tumor suppressor. PMID: 27821801
    2. Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. PMID: 26514622
    3. Consistent with the let-7 microRNA stimulatory role of TRIM71 via Lin28B polyubiquitination. PMID: 24602972
    4. poiopi poiopi i90iy9oyu8 PMID: 23892092
    5. The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing. PMID: 23097274
    6. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation PMID: 22735451
    7. Repression of human TRIM71 and the zebrafish lin-41 ortholog was abolished when predicted let-7 target sites were mutated. Regulation of TRIM71 expression by let-7 seems to have been evolutionarily conserved. PMID: 17890240

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, P-body.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Specifically expressed in testis.
  • 數據庫鏈接：

    HGNC: 32669

    KEGG: hsa:131405

    STRING: 9606.ENSP00000373272

    UniGene: Hs.113170



主站蜘蛛池模板： 漂亮人妻被中出中文字幕| 亚洲另类欧美综合在线| 日韩精品人涩人| 久久男人av资源网站| 人妻无码中字在线a| 插b内射18免费视频| 免费毛片全部不收费的| 欧洲性久久精品| 亚洲中文字幕日产乱码在线| 在线观看无码av网站永久免费| 粗大的内捧猛烈进出视频| 久久国产成人午夜av影院| 久久免费精品国产72精品| 夜精品一区二区无码a片| 久久久久麻豆v国产精华液好用吗 99久久人妻精品免费一区 | 男人的天堂av社区在线| 偷柏自拍亚洲综合在线| 国产sm重味一区二区三区| 春色校园综合人妻av| 综合激情久久综合激情| 无码人妻少妇精品无码专区漫画| 国内精品视频一区二区三区| 日本新janpanese乱熟| 欧美牲交a欧美牲交vdo18| 亚洲爆乳aaa无码专区| 亚洲成a人v欧美综合天堂| 国产久热精品无码激情| 午夜精品电影你懂的 | 久久中文字幕人妻熟女| 亚洲伊人久久综合影院| 国产96在线 | 韩国| 久久国产精品国产四虎90后| av无码免费岛国动作片不卡| 国产精品爽爽久久久久久蜜臀| 成在人线av无码免费看| 九九99久久精品在免费线18| 天干夜天天夜天干天2004年| 最新亚洲人成网站在线观看| 亚洲偷自拍国综合色帝国| 国产亚洲精品视觉盛宴| 精品国产精品国产偷麻豆|