在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM71 Antibody

TRIM71 Antibody

  • 中文名稱：
    TRIM71兔多克隆抗體
  • 貨號：
    CSB-PA173135
  • 規格：
    ￥1100
  • 圖片：
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA173135(TRIM71 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM71
  • 別名：
    2610206G21Rik antibody; Abnormal cell LINeage LIN 41 antibody; AL022943 antibody; E3 ubiquitin-protein ligase TRIM71 antibody; Gm1127 antibody; Homolog of C. elegans Lin 41 antibody; LIN 41 antibody; LIN41 antibody; LIN41_HUMAN antibody; mlin 41 antibody; Protein lin 41 homolog antibody; Protein lin-41 homolog antibody; RGD1566388 antibody; Ripply2 antibody; TRIM 71 antibody; TRIM71 antibody; Tripartite motif containing 71 antibody; Tripartite motif-containing protein 71 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human TRIM71
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:1000-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance (Probable). Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. In addition, participates in post-transcriptional mRNA repression in a miRNA independent mechanism. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1. Specific regulator of miRNA biogenesis. Binds to miRNA MIR29A hairpin and postranscriptionally modulates MIR29A levels, which indirectly regulates TET proteins expression.
  • 基因功能參考文獻：
    1. TRIM71 acts through post-transcriptional repression of Lin28B and subsequent modulation of let-7-HMGA2 signaling during tumorigenesis to potentially function as a tumor suppressor. PMID: 27821801
    2. Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. PMID: 26514622
    3. Consistent with the let-7 microRNA stimulatory role of TRIM71 via Lin28B polyubiquitination. PMID: 24602972
    4. poiopi poiopi i90iy9oyu8 PMID: 23892092
    5. The stem cell E3-ligase Lin-41 promotes liver cancer progression through inhibition of microRNA-mediated gene silencing. PMID: 23097274
    6. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation PMID: 22735451
    7. Repression of human TRIM71 and the zebrafish lin-41 ortholog was abolished when predicted let-7 target sites were mutated. Regulation of TRIM71 expression by let-7 seems to have been evolutionarily conserved. PMID: 17890240

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, P-body.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Specifically expressed in testis.
  • 數據庫鏈接：

    HGNC: 32669

    KEGG: hsa:131405

    STRING: 9606.ENSP00000373272

    UniGene: Hs.113170



主站蜘蛛池模板： 青草草97久热精品视频| 国产精品卡一卡2卡3卡4| 在线观看高清黄网站观看| 国产精品免费视频色拍拍| 免费看又色又爽又黄的国产软件| 精品亚洲欧美无人区乱码| 美女视频黄是免费| 少妇愉情理伦片高潮日本| 人与狗精品aa毛片| 久久精品人人槡人妻人人玩av| 日韩欧美激情兽交| 在线观看免费人成视频| 色噜噜狠狠一区二区三区| 强辱丰满人妻hd中文字幕| 国产无套粉嫩白浆在线| a欧美爰片久久毛片a片| 亚洲精品嫩草研究院久久 | 自拍偷自拍亚洲精品被多人伦好爽 | 真人无码作爱免费视频| 成人免费看片又大又黄| 欧洲-级毛片内射| 欧洲 亚洲 国产图片综合| 最新亚洲中文字幕在线观看| 377人体粉嫩噜噜噜| 看曰本女人大战黑人视频| 国内揄拍国内精品人妻| 国产无遮挡乱子伦免费精品| 天天天天躁天天爱天天碰| 里番本子纯肉侵犯肉全彩无码| 大肉大捧一进一出好爽app| 四虎永久在线精品免费观看视频| 欧美亚洲另类自拍丝袜| 国产av一区二区三区日韩| 精品久久久久久久免费人妻| 免费人成网站在线观看欧美| 欧美国产日韩a欧美在线观看| 中文字幕一区二区三区乱码| 国产熟女一区二区三区四区五区| 亚洲三区在线观看内射后入| 婷婷色香五月综合缴缴情| 人妻少妇精品久久|