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  4. TRIM68 Antibody

TRIM68 Antibody

  • 中文名稱：
    TRIM68兔多克隆抗體
  • 貨號：
    CSB-PA004718
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat K562 cells using SS-56 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TRIM68
  • 別名：
    TRIM68 antibody; GC109 antibody; RNF137 antibody; SS56 antibody; E3 ubiquitin-protein ligase TRIM68 antibody; EC 2.3.2.27 antibody; RING finger protein 137 antibody; RING-type E3 ubiquitin transferase TRIM68 antibody; SSA protein SS-56 antibody; SS-56 antibody; Tripartite motif-containing protein 68 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human SS-56.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as a ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
  • 基因功能參考文獻：
    1. TRIM68 targets TFG, a novel regulator of IFN production, and in doing so turns off and limits type I IFN production in response to anti-viral detection systems PMID: 24999993
    2. TRIM68 functions as a cofactor for AR-mediated transcription and is likely to be a novel diagnostic tool and a potentially therapeutic target for prostate cancer. PMID: 18451177
  • 亞細胞定位：
    Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.
  • 數據庫鏈接：

    HGNC: 21161

    OMIM: 613184

    KEGG: hsa:55128

    STRING: 9606.ENSP00000300747

    UniGene: Hs.523438



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