在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM62 Antibody

TRIM62 Antibody

  • 中文名稱：
    TRIM62兔多克隆抗體
  • 貨號：
    CSB-PA559643
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA559643(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA559643(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 cells, hepg2 cells, Primary antibody: CSB-PA559643(TRIM62 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRIM62
  • 別名：
    6330414G21Rik antibody; AI450348 antibody; DEAR1 antibody; ductal epithelium-associated RING Chromosome 1 antibody; E3 ubiquitin-protein ligase TRIM62 antibody; FLJ10759 antibody; FLJ16558 antibody; MGC115263 antibody; TRI62_HUMAN antibody; TRIM62 antibody; Tripartite motif containing 62 antibody; Tripartite motif-containing protein 62 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human TRIM62
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
  • 基因功能參考文獻(xiàn)：
    1. Results found that TRIM62 was frequently down-regulated in both human cervical cancer (CC) cells and tissues. Low expression of TRIM62 in CC tissues was associated with aggressive clinicopathological features of CC patients. Its overexpression inhibits proliferation, migration and invasion of cervical cancer cells. PMID: 27793172
    2. TRIM62 is a CARD9-binding partner. TRIM62 facilitated K27-linked poly-ubiquitination of CARD9. PMID: 26488816
    3. Low TRIM62 levels, consistent with a tumor suppressor role, represent an independent adverse prognostic factor in AML. PMID: 25248926
    4. DEAR1 is important in the regulation of the breast tumor microenvironment, polarity, and epithelial-mesenchymal transition. [Review] PMID: 25261235
    5. results provide compelling evidence that DEAR1 is a critical tumor suppressor involved in multiple human cancers and provide a novel paradigm for regulation of TGF-beta-induced EMT through DEAR1's regulation of SMAD3 protein levels PMID: 23838884
    6. these data indicate that TRIM62, a cytoplasmic protein, is a RING finger domain-dependent E3 ubiquitin ligase that catalyzes self-ubiquitination both in vitro and in vivo. PMID: 23402750
    7. DEAR1 is a predictive biomarker for early onset breast cancer. PMID: 19536324
    8. The evidence for the genetic alteration and loss of expression of DEAR1 in breast cancer and for the functional role of DEAR1 in the dominant regulation of acinar morphogenesis in 3D culture PMID: 19536326

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRIM/RBCC family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25574

    KEGG: hsa:55223

    STRING: 9606.ENSP00000291416

    UniGene: Hs.656006



主站蜘蛛池模板： 日韩国产成人无码av毛片蜜柚| 国产成人综合久久亚洲精品| yw尤物av无码国产在线观看 | 草草地址线路①屁屁影院成人| 老子午夜精品无码不卡| 欧美两根一起进3p做受视频| 久久亚洲精品中文字幕一区| 国产传媒精品1区2区3区| 色妞www精品视频| 人妻精油按摩bd高清中文字幕| 亚洲精品无码成人网站| 国产三级aⅴ在在线观看| 精品免费国产一区二区三区四区介绍 | 手机在线看永久av片免费 | 亚洲永久精品ww47| 久久青青草原国产最新片完整| 无码av喷白浆在线播放| 午夜视频在线瓜伦| 毛色毛片免费观看| 在线v片免费观看视频| 亚洲人成未满十八禁网站| 国产69精品久久久久999小说| 国产成+人+综合+亚洲欧美丁香花 欧美性黑人极品hd另类 | 欧美freesex黑人又粗又大| 欧美国产日韩a在线观看| 人人爽人人爽人人片a免费 | 国产亚洲精品久久久久四川人| 天堂在/线资源中文在线| 亚洲成av人片天堂网老年人| 人妻熟女一区二区三区app下载 | 成年无码a√片在线观看| 欧美一区二区三区啪啪| 国产成人啪精品视频免费网站软件| 无码人妻一区二区三区免费n鬼逝 好爽好湿好硬好大免费视频 | 国产一区二区三区四区精华| 国产精品毛片更新无码| 四虎成人精品在永久免费| 亚洲熟女综合一区二区三区| 美国特级a毛片免费网站| 日韩精品成人一区二区三区 | 啦啦啦www在线观看免费视频 |