在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM62 Antibody

TRIM62 Antibody

  • 中文名稱：
    TRIM62兔多克隆抗體
  • 貨號：
    CSB-PA559643
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA559643(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA559643(TRIM62 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 231 cells, hepg2 cells, Primary antibody: CSB-PA559643(TRIM62 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRIM62
  • 別名：
    6330414G21Rik antibody; AI450348 antibody; DEAR1 antibody; ductal epithelium-associated RING Chromosome 1 antibody; E3 ubiquitin-protein ligase TRIM62 antibody; FLJ10759 antibody; FLJ16558 antibody; MGC115263 antibody; TRI62_HUMAN antibody; TRIM62 antibody; Tripartite motif containing 62 antibody; Tripartite motif-containing protein 62 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human TRIM62
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors; leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.
  • 基因功能參考文獻(xiàn)：
    1. Results found that TRIM62 was frequently down-regulated in both human cervical cancer (CC) cells and tissues. Low expression of TRIM62 in CC tissues was associated with aggressive clinicopathological features of CC patients. Its overexpression inhibits proliferation, migration and invasion of cervical cancer cells. PMID: 27793172
    2. TRIM62 is a CARD9-binding partner. TRIM62 facilitated K27-linked poly-ubiquitination of CARD9. PMID: 26488816
    3. Low TRIM62 levels, consistent with a tumor suppressor role, represent an independent adverse prognostic factor in AML. PMID: 25248926
    4. DEAR1 is important in the regulation of the breast tumor microenvironment, polarity, and epithelial-mesenchymal transition. [Review] PMID: 25261235
    5. results provide compelling evidence that DEAR1 is a critical tumor suppressor involved in multiple human cancers and provide a novel paradigm for regulation of TGF-beta-induced EMT through DEAR1's regulation of SMAD3 protein levels PMID: 23838884
    6. these data indicate that TRIM62, a cytoplasmic protein, is a RING finger domain-dependent E3 ubiquitin ligase that catalyzes self-ubiquitination both in vitro and in vivo. PMID: 23402750
    7. DEAR1 is a predictive biomarker for early onset breast cancer. PMID: 19536324
    8. The evidence for the genetic alteration and loss of expression of DEAR1 in breast cancer and for the functional role of DEAR1 in the dominant regulation of acinar morphogenesis in 3D culture PMID: 19536326

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRIM/RBCC family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25574

    KEGG: hsa:55223

    STRING: 9606.ENSP00000291416

    UniGene: Hs.656006



主站蜘蛛池模板： 中文字幕卡二和卡三的视频| 无码一区二区三区av免费蜜桃| 欧美日本特级婬片视频| 99热在线精品国产观看| 肉体裸交137日本大胆摄影| 免费观看成人欧美www色| 少妇被爽到高潮喷水久久欧美精品| 国产乱来乱子视频| 高大丰满熟妇丰满的大白屁股| 欧美日韩免费专区在线| 国产精品sm捆绑调教视频| 夜夜欢性恔真人免费视频| 军人粗大的内捧猛烈进出视频| 久久综合伊人77777麻豆| 久久久久人妻一区精品色欧美 | 色悠久久久久综合网国产| 美女视频黄是免费| www国产精品内射| 午夜视频在线在免费| 国产av国片精品有毛| 国产男女猛烈无遮挡免费视频网站| 亚洲 小说区 图片区 都市| 日韩免费无码一区二区视频| 国产色青青视频在线观看撒| 亚洲伊人色欲综合网无码中文| 欧美丰满熟妇xxxx性| 中文字幕在线观看亚洲视频| 成在人线av无码免费高潮水老板 | 性色欲网站人妻丰满中文久久不卡| 色护士极品影院| 国产精品亚洲精品一区二区 | 午夜dv内射一区二区| 亚洲乱码国产乱码精品精| 久久精品中文騷妇女内射| 真实人与人性恔配视频| 人妻系列影片无码专区| 野花社区视频www官网| 国产极品美女到高潮| 伊人久久丁香色婷婷啪啪| 中文字幕丝袜第1页| 日日噜噜夜夜狠狠va视频v|