TRIM4 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TRIM4 Polyclonal antibody
Uniprot No.：

Q9C037
基因名：

TRIM4
別名：

RING finger protein 87 antibody; RNF 87 antibody; RNF87 antibody; TRIM4 antibody; TRIM4_HUMAN antibody; Tripartite motif containing 4 antibody; Tripartite motif protein 4 antibody; Tripartite motif protein TRIM4 antibody; Tripartite motif-containing protein 4 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human E3 ubiquitin-protein ligase TRIM4 protein (1-118AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor DDX58, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
基因功能參考文獻：
1. TRIM4 is an important regulator of the virus-induced interferon induction pathways by mediating RIG-I for K63-linked ubiquitination. PMID: 24755855
2. ZNF198-FGFR1 is associated with phosphorylation of several proteins including SSBP2, ABL, FLJ14235, CALM and TRIM4 proteins. PMID: 19658100
亞細胞定位：

Cytoplasm.
蛋白家族：

TRIM/RBCC family
數據庫鏈接：

HGNC: 16275

KEGG: hsa:89122

STRING: 9606.ENSP00000348216

UniGene: Hs.50749

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