在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRIM3 Antibody

TRIM3 Antibody

  • 中文名稱：
    TRIM3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006667
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO cells using TRIM3 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRIM3
  • 別名：
    BERP antibody; Brain expressed ring finger antibody; Brain-expressed RING finger protein antibody; FLJ16135 antibody; HAC1 antibody; RING finger protein 22 antibody; RING finger protein 97 antibody; RNF22 antibody; RNF97 antibody; Trim3 antibody; TRIM3_HUMAN antibody; Tripartite motif containing 3 antibody; Tripartite motif protein TRIM3 antibody; Tripartite motif-containing protein 3 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human TRIM3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Positively regulates motility of microtubule-dependent motor protein KIF21B.
  • 基因功能參考文獻(xiàn)：
    1. TRIM3 plays a tumor-suppressing role in the regulation of liver cancer development by reducing cell proliferation through cell cycle arrest at the G0/G1 phase. PMID: 28950898
    2. The results of quantitative real-time RT-PCR and western blotting showed that the TRIM3 expression was very low in five cervical cancer cell lines. The TRIM3 overexpression weakened cell viability, and promote apoptosis of C-33A and SiHa cells in vitro, and inhibit tumor growth in vivo, which suggested that TRIM3 could reduce proliferation of cervical cancer cells. PMID: 29524410
    3. TRIM3 exerted an anti-proliferation role in rheumatoid arthritis fibroblast-like synoviocytes via p38 signaling pathway. PMID: 28259936
    4. results support a novel role for Brat/TRIM3 in maintaining stem cell equilibrium and suppressing tumor growth by regulating NICD nuclear transport PMID: 26893479
    5. TRIM3 functions as a tumour suppressor in CRC progression. This tumour-suppressive function is exerted partially through regulation of p53 protein. PMID: 26691157
    6. Studies indicate most-studied TRIpartite Motif (TRIM)-NHL proteins TRIM2, TRIM3, TRIM32 and TRIM71, and their mutations have been linked to diseases. PMID: 26514622
    7. TRIM3 may play a significant role in hepatocellular carcinoma progression.TRIM3 is downregulated in hepatocellular carcinoma at both the mRNA and protein levels and that low TRIM3 expression is correlated with an unfavorable prognosis. PMID: 24994609
    8. TRIM3 acts as a tumor suppressor in GBM by restoring asymmetric cell division. PMID: 24947043
    9. Data indicate TRIM3 and p21 interact in cells. PMID: 23318451
    10. TRIM63 is a candidate for genes mediating the glucocorticoid-induced promotion of osteoblastic differentiation. PMID: 20173306
    11. brain-expressed RING finger protein (BERP) is a gene whose expression is up-regulated in a p53-dependent manner PMID: 20543135
    12. the endosome-associated protein hrs is a subunit of a protein complex containing actinin-4, BERP, and myosin V that is necessary for efficient TfR recycling but not for EGFR degradation PMID: 15772161
    13. Loss of heterozygosity of chromosome segment 11p15.5 in malignant gliomas suggests TRIM3 as a candidate brain tumor suppressor gene. PMID: 19250537

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Early endosome. Golgi apparatus, trans-Golgi network. Cell projection, dendrite.
  • 蛋白家族：
    TRIM/RBCC family
  • 組織特異性：
    Expressed in brain, heart, uterus and testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 10064

    OMIM: 605493

    KEGG: hsa:10612

    STRING: 9606.ENSP00000340797

    UniGene: Hs.591992



主站蜘蛛池模板： 天堂资源在线www在线观看| 国产区精品系列在线观看| 国产成人无码免费视频麻豆| 四虎www永久在线精品| 影音先锋每日av色资源站| 精品免费国产一区二区三区四区 | 少妇大叫太大太爽受不了| 人妻 色综合网站| 国语国产精精品国产国语清晰对话 | 亚洲一区在线日韩在线尤物| 中文字幕资源网| 久久久精品日本一区二区三区| 欧美又大粗又爽又黄大片视频| 国产好爽…又高潮了毛片| 18禁亚洲深夜福利入口| 国产男女免费完整视频网页| 亚洲国产成人无码网站大全| 欧美性欧美巨大黑白大战| 美国特级a毛片免费网站| 天堂…中文在线最新版在线| 成人做爰www网站视频| 日韩国产精品无码一区二区三区| 欧美伦费免费全部午夜最新| 国语自产偷拍精品视频偷| 欧美激情一区二区三区高清视频| 国产美女a做受大片观看| 一本色道久久88精品综合| 色翁荡熄又大又硬又粗又动态图| 亚洲精品动漫免费二区| 日韩综合亚洲色在线影院| 亚洲色无码中文字幕在线| 在线看片人成视频免费无遮挡| 最新69国产成人精品视频免费| 日韩a人毛片精品无人区乱码| 天天av天天翘天天综合网色鬼| 成人精品视频一区二区三区| 欧洲极品无码一区二区三区| 日本人妻精品免费视频| 99久久99久久精品免费看蜜桃| 国产亚洲精品97在线视频一| 亚洲制服丝中文字幕|