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  4. TRAM2 Antibody

TRAM2 Antibody

  • 中文名稱：
    TRAM2兔多克隆抗體
  • 貨號：
    CSB-PA624011LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA624011LA01HU at dilution of 1:100
    • Immunofluorescent analysis of MCF-7 cells using CSB-PA624011LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TRAM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRAM2
  • 別名：
    TRAM2; KIAA0057; Translocating chain-associated membrane protein 2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Translocating chain-associated membrane protein 2 protein (316-370AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TRAM2 Antibody (CSB-PA624011LA01HU)，的標記方式是Non-conjugated。對于TRAM2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA624011LB01HU TRAM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA624011LC01HU TRAM2 Antibody, FITC conjugated
    Biotin CSB-PA624011LD01HU TRAM2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
  • 基因功能參考文獻：
    1. TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon PMID: 14749390
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TRAM family
  • 數據庫鏈接：

    HGNC: 16855

    OMIM: 608485

    KEGG: hsa:9697

    STRING: 9606.ENSP00000182527

    UniGene: Hs.520182



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