在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRAM1 Antibody

  • 中文名稱:
    TRAM1兔多克隆抗體
  • 貨號:
    CSB-PA024221GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    TRAM1 antibody; TRAM antibody; Translocating chain-associated membrane protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TRAM1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilayer in the vicinity of the lateral gate of the SEC61 channel, thereby facilitating ER protein transport. Intimately associates with transmembrane (TM) domain of nascent membrane proteins during the entire integration process into the ER membrane. Associates with the second TM domain of G-protein-coupled receptor opsin/OPSD nascent chain in the ER membrane, which may facilitate its integration into the membrane. Under conditions of ER stress, participates in the disposal of misfolded ER membrane proteins during the unfolded protein response (UPR), an integrated stress response (ISR) pathway, by selectively retrotranslocating misfolded ER-membrane proteins from the ER into the cytosol where they are ubiquitinated and degraded by the proteasome.; (Microbial infection) In case of cytomegalovirus infection, participates in US2- and US11-mediated ER-to-cytosol retrotranslocation and subsequent degradation of major histocompatibility complex (MHC) class I heavy chains, thereby decreasing the immune detection by cytotoxic T-cells.
  • 基因功能參考文獻:
    1. TRAM1 protect HepG2 cells from palmitate-induced insulin resistance. The protection of TRAM1 to HepG2 cells is through endoplasmic reticulum stress-JNK pathway. PMID: 25600807
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    TRAM family
  • 數據庫鏈接:

    HGNC: 20568

    OMIM: 605190

    KEGG: hsa:23471

    STRING: 9606.ENSP00000262213

    UniGene: Hs.491988



主站蜘蛛池模板: 精品国产卡一卡2卡3卡| 国产午费午夜福利200集| 夜夜躁狠狠躁日日躁202| 亚洲精品国产一区二区图片| 亚洲中文字幕无码久久| 午夜福利伦伦电影理论片在线观看| 成人h动漫精品一区二区无码| 一区二区亚洲精品国产精华液| 国产精品自在线拍国产| 久久久青草青草免费看| 久久国产色欲av38| 久久精品国产免费播| 中文字幕亚洲无线码| 国产成人免费爽爽爽视频| 国产精品卡1卡2卡三卡四| 亚洲乱码卡一卡二卡| 国产成人无码a区在线观看视频app| 一本色道久久88亚洲精品综合| 人妻无码一区二区三区四区| 国产日韩精品一区二区三区在线| 女人18毛片水真多免费看| 国产情侣激情在线视频| 国产精品调教视频一区| 日本饥渴人妻欲求不满| 国产精品久久久久久亚洲影视| 亚洲欲色欲色xxxxx在线观看| 韩国 日本 亚洲 国产 不卡| 欧美日韩亚洲国产欧美电影| 欧美另类videossexo高潮| 99久久精品日本一区二区免费| 国产午夜精品一区二区三区老 | 国产肉体xxxx裸体784大胆| 中国浓毛少妇毛茸茸| 亚欧免费无码aⅴ在线观看蜜桃| 麻豆国产丝袜白领秘书在线观看| 狠狠色丁香久久综合婷婷| 中文字幕网伦射乱中文| 欧美牲交a欧美牲交aⅴ图片| 日本午夜看x费免| 欧美人与动牲交zooz| 日韩欧美亚洲综合久久|