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TRAFD1 Antibody, HRP conjugated

  • 中文名稱：
    TRAFD1兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA024156LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TRAFD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TRAFD1
  • 別名：
    FLN29 antibody; FLN29 gene product antibody; Protein FLN29 antibody; TRAD1_HUMAN antibody; TRAF type zinc finger domain containing 1 antibody; TRAF type zinc finger domain containing protein 1 antibody; TRAF-type zinc finger domain-containing protein 1 antibody; TRAFD 1 antibody; TRAFD1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human TRAF-type zinc finger domain-containing protein 1 protein (2-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
  • 基因功能參考文獻：
    1. FLN29 is a new negative feedback regulator of TLR signaling PMID: 16221674
    2. FLN29, in addition to playing a negative regulatory role in the TLR4 signaling pathway, negatively regulates the RIG-I-like helicase signaling pathway at the level of IPS-1/TRAF6 and IPS-1/TRAF3 complexes PMID: 18849341
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24808

    OMIM: 613197

    KEGG: hsa:10906

    STRING: 9606.ENSP00000257604

    UniGene: Hs.5148



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