在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRAF3IP1 Antibody

TRAF3IP1 Antibody

  • 中文名稱：
    TRAF3IP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA969451
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse thymus tissue, Primary antibody: CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRAF3IP1
  • 別名：
    Interleukin 13 receptor alpha 1 binding protein 1 antibody; Interleukin-13 receptor alpha 1-binding protein 1 antibody; Microtubule interacting protein that associates with TRAF3 antibody; Microtubule-interacting protein associated with TRAF3 antibody; MIP T3 antibody; MIP-T3 antibody; MIPT3 antibody; MIPT3_HUMAN antibody; TNF receptor associated factor 3 interacting protein 1 antibody; TRAF3-interacting protein 1 antibody; Traf3ip1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TRAF3IP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Mutations in TRAF3IP1 are identified in patients with nephronophthisis and retinal degeneration. The identified mutations result in mild ciliary defects in patients and reveal a role of IFT54 as a negative regulator of microtubule stability via MAP4. PMID: 26487268
    2. MIP-T3 functions as a negative regulator of the innate type I interferon response by preventing TRAF3 from forming protein complexes with critical downstream transducers and effectors of antiviral response. PMID: 22079989
    3. Data show that MIP-T3 protein level is highly regulated; mainly mediated by the ubiquitin-proteasome system. PMID: 21510943
    4. The interaction of MIP-T3 with both actin filaments and microtubule suggested that MIP-T3 may play an important role in regulation of cytoskeleton dynamics in cells. PMID: 20391533
    5. These results suggest that MIP-T3 is a novel inhibitor of IL-13 signaling and may be a useful molecule in ameliorating various conditions in which IL-13 plays a central role. PMID: 12935900

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Senior-Loken syndrome 9 (SLSN9)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    TRAF3IP1 family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17861

    OMIM: 607380

    KEGG: hsa:26146

    STRING: 9606.ENSP00000362424

    UniGene: Hs.631898



主站蜘蛛池模板： 国产手机在线精品| 久久久久久久综合日本| 午夜dj在线观看高清在线视频完整版| 久久久噜噜噜www成人网| 国产成人精品综合久久久| 精品无码中文视频在线观看 | 国产精品成人3p一区二区三区| 亚洲 欧美 国产 日韩 中文字幕| 精品www日韩熟女人妻| 久久超碰精品一夜七次郎| 人妻免费一区二区三区最新| 亚洲另类欧美小说图片区| 体验区试看120秒啪啪免费| 国产成人av 综合 亚洲| 国产美女在线精品免费观看网址| 国产精品自在在线午夜| 中文字幕久久综合伊人| 亚洲乱色伦图片区小说| 精品国产电影久久九九| 亚洲午夜成人av电影 | 日韩精品人妻系列无码专区| 桃花综合久久久久久久久久网| 午夜性色吃奶添下面69影院| 久久www免费人成_看片老司机| 99精品众筹模特自拍视频| 一区二区三区无码被窝影院| 国产精品高清视亚洲中文| 亚洲日产韩国一二三四区| 亚洲精品久久中文字幕| 在线视频免费无码专区| 思思99热久久精品在线6| 中文字幕日韩欧美一区二区三区| 男女啪啪做爰高潮免费网站| 青草av久久一区二区三区| 亚洲欧洲日本精品专线| 18禁黄污吃奶免费看网站| 97se亚洲国产综合自在线尤物| 久久久久久无码精品人妻a片软件| 老色鬼永久精品网站| 久久天天躁狠狠躁夜夜躁2014| 国产美女视频免费观看的网站|