在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TRAF3IP1 Antibody

TRAF3IP1 Antibody

  • 中文名稱：
    TRAF3IP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA969451
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse thymus tissue, Primary antibody: CSB-PA969451(TRAF3IP1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRAF3IP1
  • 別名：
    Interleukin 13 receptor alpha 1 binding protein 1 antibody; Interleukin-13 receptor alpha 1-binding protein 1 antibody; Microtubule interacting protein that associates with TRAF3 antibody; Microtubule-interacting protein associated with TRAF3 antibody; MIP T3 antibody; MIP-T3 antibody; MIPT3 antibody; MIPT3_HUMAN antibody; TNF receptor associated factor 3 interacting protein 1 antibody; TRAF3-interacting protein 1 antibody; Traf3ip1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TRAF3IP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis.
  • 基因功能參考文獻(xiàn)：
    1. Mutations in TRAF3IP1 are identified in patients with nephronophthisis and retinal degeneration. The identified mutations result in mild ciliary defects in patients and reveal a role of IFT54 as a negative regulator of microtubule stability via MAP4. PMID: 26487268
    2. MIP-T3 functions as a negative regulator of the innate type I interferon response by preventing TRAF3 from forming protein complexes with critical downstream transducers and effectors of antiviral response. PMID: 22079989
    3. Data show that MIP-T3 protein level is highly regulated; mainly mediated by the ubiquitin-proteasome system. PMID: 21510943
    4. The interaction of MIP-T3 with both actin filaments and microtubule suggested that MIP-T3 may play an important role in regulation of cytoskeleton dynamics in cells. PMID: 20391533
    5. These results suggest that MIP-T3 is a novel inhibitor of IL-13 signaling and may be a useful molecule in ameliorating various conditions in which IL-13 plays a central role. PMID: 12935900

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Senior-Loken syndrome 9 (SLSN9)
  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    TRAF3IP1 family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17861

    OMIM: 607380

    KEGG: hsa:26146

    STRING: 9606.ENSP00000362424

    UniGene: Hs.631898



主站蜘蛛池模板： 亚洲第一成年免费网站| 久久亚洲人成电影网| 无码国产片观看| 久久成人伊人欧洲精品| 国产成人综合一区人人| 青青草av国产精品| 男女下面进入的视频免费午夜| 国产精品高清一区二区三区| 熟妇人妻中文av无码| 免费无码一区二区三区蜜桃大| 2021最新精品国自产拍视频| 热re99久久6国产精品免费| 国产精品久久久久久熟妇吹潮软件| 熟女人妻视频| 国产精品污www在线观看| 亚洲国产精品成人精品无码区在线| 国产精品高潮呻吟av久久小说| 国产精品免费视频色拍拍| 久久久国产精品人人片| 少妇做爰免费视频了| 人人妻人人澡人人爽国产一区| 无码专区亚洲综合另类| 亚洲乱码卡一卡二卡新区仙踪木木| 国产av一区二区精品久久| 人人妻人人澡人人爽| 色先锋资源久久综合5566| 性中国妓女毛茸茸视频| 少妇愉情理伦片bd| 亚洲成a人片77777kkkk| 男女车车的车车网站w98免费| 日韩制服国产精品一区| 久久97超碰色中文字幕总站| 国产乱人伦av麻豆网| 青娱乐极品视觉盛宴av| 亚洲日韩精品射精日| 亚洲国产品综合人成综合网站| 久久精品国产精品亚洲毛片| 人妻丰满熟妇av无码区不卡| 成人免费无遮挡在线播放| 最新国产成人无码久久| 丰满的少妇xxxxx青青青|