在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TRAC Antibody, Biotin conjugated

  • 中文名稱:
    TRAC兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA024144LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TRAC Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    TRAC antibody; TCRA antibody; T cell receptor alpha constant antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human T cell receptor alpha constant protein (1-140AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Constant region of T cell receptor (TR) alpha chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70. In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome. The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation. The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity.
  • 相關疾病:
    Immunodeficiency 7 (IMD7)
  • 亞細胞定位:
    Cell membrane.
  • 數據庫鏈接:

    HGNC: 12029

    OMIM: 186880

    UniGene: Hs.74647



主站蜘蛛池模板: 国产mv在线天堂mv免费观看| 香蕉视频在线观看亚洲| 又粗又黄又硬又爽的免费视频| 久久久这里只有免费精品| 国产初高中生粉嫩无套第一次| 天堂va欧美ⅴa亚洲va| 久久精品人人做人人爽| 国内精品久久久久久中文字幕| 影音先锋在线亚洲网站| 国产片av片永久免费观看| 国产在线视频一区二区三区| 狠狠色噜噜狠狠狠狠av| 丁香婷婷综合久久来来去| 天天天天噜在线视频| 国产精品成人精品久久久| 女人爽得直叫免费视频| 无码一区18禁3d| 亚洲成av人片在线观看高清| 成人综合婷婷国产精品久久蜜臀 | 国产无遮挡又爽又黄大胸免费| 艳妇乳肉豪妇荡乳在线观看| 久久久久人妻精品一区三寸蜜桃 | 国产+日韩+另类+视频一区| 国产成人综合一区人人| 一边吃奶一边摸做爽视频| 国产av综合影院| 亚洲精品无码久久久久yw | 人妻少妇偷人精品视频| 国产做无码视频在线观看| 久久久久亚洲精品天堂| 午夜激成人免费视频在线观看 | 国产免费一区二区三区在线观看| 小说区 图片区色 综合区| 色综合久久久无码中文字幕| 在线观看的av免费网站| 欧美三级午夜理伦三级| 国产午夜伦鲁鲁| 好日子在线观看视频大全免费动漫| 日本无码人妻一区二区色欲| 日韩av无码中文字幕| 亚洲国产欧美国产综合久久|