在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNR Antibody

TNR Antibody

  • 中文名稱：
    TNR兔多克隆抗體
  • 貨號：
    CSB-PA024023GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Janusin antibody; MGC149328 antibody; Restrictin antibody; Tenascin R (restrictin, janusin) antibody; Tenascin-R antibody; TENR_HUMAN antibody; TN-R antibody; Tnr antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human TNR-Specific
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance.
  • 基因功能參考文獻：
    1. Two genes, TNR (and TNK2), were found to have genetic variations linked to familial Parkinson's Disease. PMID: 26595808
    2. TnC and TnR play important roles in nervous and immune systems. [Review] PMID: 23269478
    3. citation presents comparison with human gene. PMID: 12927810
    4. results show that tenascin-R expression is tightly regulated in a spatiotemporal manner during brain development, especially cortical plate formation; its pattern of expression suggests a role for tenascin-R in corticogenesis PMID: 21456020
    5. KIAA0510, the 3'-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas PMID: 20202125
    6. The researchers found evidence that the tenascin R gene is a potential susceptiblity or marker gene for IgA nephropathy. PMID: 19890582
    7. Tenascin R is expressed and glycosylated in neurons PMID: 14681222
    8. An extracellular matrix molecule TNR and its associated carbohydrate human natural killer cell glycan (HNK-1) provide conditions beneficial for induction of long-term potentiation in the hippocampus. PMID: 17537973
    9. Clinical trial of gene-disease association, gene-gene interaction, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 19573479

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Tenascin family
  • 組織特異性：
    Brain specific.
  • 數據庫鏈接：

    HGNC: 11953

    OMIM: 601995

    KEGG: hsa:7143

    STRING: 9606.ENSP00000263525

    UniGene: Hs.659864



主站蜘蛛池模板： а√天堂8资源在线官网| 97久久久人妻一区精品| 中文字幕卡二和卡三的视频| 亚洲日本在线在线看片| 久久午夜无码鲁丝片直播午夜精品 | 国产又粗又黄又爽的大片| 色无码av在线播放| 特大巨黑吊xxxx高潮| 亚洲国产成人久久综合三区| 国产精品美女久久久浪潮av | 久久久久久无码精品人妻a片软件 999久久久精品国产消防器材 | 国产综合有码无码中文字幕| 亚洲精品一区二区三区中文字幕| 性裸交a片一区二区三区| 亚洲高清无在码在线电影| 日本丰满岳乱妇在线观看| 久久精品视频在线看| www国产亚洲精品| 1000部又爽又黄无遮挡的视频| 欧美特黄特色三级视频在线观看| а天堂中文在线官网在线| 天天色影网| 在线播放免费人成毛片试看| 亚洲色无码中文字幕在线| 国产精品久久久久久久久ktv| 亚洲最大的成人网站| 国产无遮挡又黄又爽奶头| 国内精品久久久久影院日本| 麻豆 美女 丝袜 人妻 中文| 国产爆乳无码av在线播放| 人妻系列无码专区无码中出| 中文精品久久久久人妻不卡| 国产suv精品一区二区6| 欧美人与动zozo在线播放| 日本黄页网站免费大全| www国产成人免费观看视频| 色多多成视频人在线观看| 久久久综合九色合综| 无罩大乳的熟妇正在播放| 亚洲精品国产综合久久一线| 婷婷五月综合色中文字幕 |