在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TNNI1 Antibody

  • 中文名稱:
    TNNI1兔多克隆抗體
  • 貨號(hào):
    CSB-PA024011GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    TNNI1
  • 別名:
    2700018B22Rik antibody; AI747285 antibody; DKFZp451O223 antibody; si:dz182n13.3 antibody; slow skeletal muscle antibody; slow-twitch isoform antibody; SSTNI antibody; TNN1 antibody; Tnni1 antibody; TNNI1_HUMAN antibody; Troponin I antibody; Troponin I slow skeletal muscle antibody; Troponin I slow twitch isoform antibody; troponin I type 1 (skeletal; slow) antibody; Troponin I; slow isoform antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TNNI1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
  • 基因功能參考文獻(xiàn):
    1. Ultrasensitive troponin I was detectable in almost all individuals of a study sample reflecting middle-aged to elderly European general population. Ultrasensitive troponin concentrations exhibit an independent, graded, positive relation with incident CHD [coronary heart disease]. PMID: 28585121
    2. Measuring mean platelet volume in conjunction with troponin I levels improves the diagnostic value of troponin I in acute coronary syndrome. PMID: 27524214
    3. CT-1 was found to be associated with Tn-I, which is used to detect myocardial damage after OPCAB surgery. CT-1 may also be used to detect myocardial damage. PMID: 26334851
    4. TNNI3K is a cardiac-specific gene, encoding a cardiac troponin I-interacting MAP kinase. In mice, Tnni3k is shown to play an important role in the regulation of cardiac differentiation and cardiac contractility PMID: 25791106
    5. sTnI as a sensitive marker of skeletal muscle injury. PMID: 22323298
    6. Elevations of troponin I and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are common in patients with atrial fibrillation and independently related to increased risks of stroke and mortality. PMID: 22374183
    7. Elevated post-operative troponin 1 levels predict long-term mortality in older patients undergoing emergency orthpedic surgery. PMID: 19811558
    8. Evaluated the prevalence of TNN13 gene mutations in sudden death caused by cardiomyopathy (CM); in dilated CM cases, a new missense mutation Pro16Thr was detected. A single nucleotide polymorphism at -8 position of intron 3 was identified. PMID: 20817590
    9. troponin I phosphorylation has a role in protein kinase C-mediated enhanced contractile performance of myocytes PMID: 12815045
    10. MEF2 activation of the troponin I slow enhancer is repressed by hMusTRD1alpha1 PMID: 12857748
    11. Low expression of ssTnI was found in 60% of patients in sinus rhythm or paroxysmal AF and in 8% of patients with chronic AF. Relative ssTnI mRNA expression was significantly lower in patients with AF than in those in sinus rhythm. PMID: 15289369
    12. A biological marker of myocardial injury, but may also be increased after a grand mal seizure. PMID: 15367881
    13. These results suggest that this R21C mutation in TnI affects the Ca(2+)-sensitizing effect of Tn, the ability of TnI to be readily phosphorylated by PKA and the stability of TnI to calpain. PMID: 16005017
    14. Relationship between myocardial injury, assessed by cardiac troponin I (cTnI) levels, and outcome in selected critically ill patients without acute coronary syndromes or cardiac dysfunction PMID: 16236952
    15. This marker in paatients with heart failure and anemia identifies patients at particularly high risk mortality. PMID: 16338262
    16. Increased serum levels of troponin I is associated with calcinosis and coronary Artery Stenosis PMID: 16358990
    17. The plasma levels of CRP and troponin I were also significantly higher in this group of nine patients, and correlated with urinary protein excretion. PMID: 16916777
    18. A revised method of troponin exchange in pemeabilized cardiac trabeculae using vanadate: functional consequences of a HCM-causing mutation in troponin I. PMID: 17051347
    19. a localized N-terminal region of TnI comprised of amino acids 33-80, which interacts with C-terminal regions of cTnC and cTnT, is of particular significance in transducing signaling of thin filament activation by strong cross-bridges PMID: 17099250

    顯示更多

    收起更多

  • 蛋白家族:
    Troponin I family
  • 組織特異性:
    Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11945

    OMIM: 191042

    KEGG: hsa:7135

    STRING: 9606.ENSP00000337022

    UniGene: Hs.320890



主站蜘蛛池模板: 国产xxxx视频在线观看| 国产免费爽爽视频在线观看| 99国产揄拍国产精品人妻| 国产性天天综合网| 日本高清在线一区二区三区| 在线欧美日韩制服国产| 国产美女口爆吞精普通话| 热久久视久久精品18| 久久亚洲中文字幕无码| 综合三区后入内射国产馆| 高大丰满欧美熟妇hd| 亚洲а∨天堂男人无码2008| 久久人妻少妇嫩草av无码专区| 51妺嘿嘿午夜福利| 久久久久 亚洲 无码 av 专区| 亚欧av无码乱码在线观看性色| 无遮挡又黄又刺激的视频| 国产极品白嫩精品| 国产免费人成网站x8x8| 无码人妻精品一区二区三区蜜桃| 国产肉体ⅹxxx137大胆| 大肉大捧一进一出视频出来呀| 日本乱理伦片在线观看中文| 一二区成人影院电影网| 成人国产欧美大片一区| 久99视频精品免费观看福利| 免费乱码人妻系列无码专区| 中文区中文字幕免费看| av无码中文一区二区三区四区| 99久久国产成人免费网站| 亚洲第一无码xxxxxx| 国产精品一卡二卡三卡| 辽宁熟女高潮狂叫视频| 乱码国产丰满人妻www| 亚洲熟妇av乱码在线观看| 乱人伦无码中文视频在线| 国内午夜熟妇又乱又伦| 成人国产亚洲精品a区天堂 | 国产在线一区二区av视频| 欧美大胆作爱视频欣赏人体| 中文字幕精品久久久久人妻|