在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNKS1BP1 Antibody

TNKS1BP1 Antibody

  • 中文名稱：
    TNKS1BP1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA871634LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA871634LA01HU diluted at 1:300 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA871634LA01HU diluted at 1:300 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA871634LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TNKS1BP1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TNKS1BP1
  • 別名：
    182 kDa tankyrase 1 binding protein antibody; 182 kDa tankyrase-1-binding protein antibody; FLJ45975 antibody; KIAA1741 antibody; TAB182 antibody; Tankyrase 1 binding protein 1 182 kDa antibody; Tankyrase 1 binding protein 1 antibody; Tankyrase 1 binding protein of 182 kDa antibody; TB182_HUMAN antibody; Tnks1bp1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human 182 kDa tankyrase-1-binding protein (271-375AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，TNKS1BP1 Antibody (CSB-PA871634LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于TNKS1BP1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA871634LB01HU TNKS1BP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA871634LC01HU TNKS1BP1 Antibody, FITC conjugated
    Biotin CSB-PA871634LD01HU TNKS1BP1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 基因功能參考文獻(xiàn)：
    1. Results found that TNKS1BP1 was upregulated in human lung adenocarcinoma tissues, and regulates genome stability, mainly through affecting the homologous recombination pathway of DNA double-strand breaks. These results indicate that overexpression of TNKS1BP1 might affect the outcomes of lung cancer patients to chemotherapy and radiotherapy. PMID: 28058814
    2. In clinical samples of pancreatic cancer, TNKS1BP1 expression was reduced in invasive regions. We propose that the tankyrase-TNKS1BP1 axis constitutes a posttranslational modulator of cell invasion whose aberration promotes cancer malignancy PMID: 28202517
    3. TNKS1BP1 has a role in DNA double-strand break repair though DNA-PKcs autophosphorylation which is dependent on PARP-1 PMID: 25749521
    4. The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182). PMID: 11854288
    5. Identification of a tankyrase-binding motif in this protein. PMID: 12080061
    6. Data show that tankyrase 1 inhibition in human cancer cells enhances telomere shortening by a telomerase inhibitor and hastens cell death. PMID: 15652747
    7. We also demonstrate a requirement for tankyrase-1 in the assembly of bipolar spindles, and identify the spindle-pole protein NuMA as a substrate for covalent modification by tankyrase-1. PMID: 16244666
    8. TNKS-1 mRNA in urine sediment from patients with bladder TCC correlated with tumor stage, and higher preoperative levels were associated with increased risk of early recurrence. PMID: 17617028

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm, cytoskeleton. Chromosome. Note=Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
  • 組織特異性：
    Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19081

    OMIM: 607104

    KEGG: hsa:85456

    STRING: 9606.ENSP00000350990

    UniGene: Hs.530730



主站蜘蛛池模板： 女人被狂c躁到高潮视频| 韩国国内大量揄拍精品视频| 亚洲乱色熟女一区二区三区丝袜| 蜜桃臀无码内射一区二区三区 | 最新欧美精品一区二区三区| 波多野结衣在线观看一码| 国产伦精品一区二区三区妓女下载| 亚洲精品久久久久久久久久久捆绑 | 国产玉足脚交极品在线播放| 日本大片免费观看视频| 精品欧美成人高清在线观看| 99精品国产成人一区二区| 少妇愉情理伦片高潮日本| 香蕉精品亚洲二区在线观看| 在线天堂资源www在线污| 夜夜夜夜猛噜噜噜噜噜| 久久精品中文字幕无码绿巨人| 欧美成人va免费大片视频| 男女性爽大片视频免费看| 免费观看又污又黄的网站| 久久国产36精品色熟妇| 国产美女爽到喷出水来视频| 亚洲精品乱码久久久久蜜桃| 欧美三根一起进三p| 日本老熟妇乱| 欧美性video高清精品| 国产精品毛多多水多| 日韩成av人片在线观看| 久久tv中文字幕首页| 免费播放婬乱男女婬视频国产| 亚洲精品无码久久| 99re热这里只有精品视频| 中文字幕久久久久人妻中出| 国产精品卡一卡2卡3卡4| 免费无码黄网站在线看| 狠狠做深爱婷婷久久综合一区| 午夜福利国产成人a∨在线观看| 亚洲人成黄网站69影院| 欧美成人免费一区二区| 人妻少妇精品视频无码综合| 中文字幕av无码免费久久|