在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TNFRSF13C Antibody

  • 中文名稱:
    TNFRSF13C兔多克隆抗體
  • 貨號:
    CSB-PA853495LA01HU
  • 規格:
    ¥440
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TNFRSF13C Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    B cell activating factor receptor antibody; B-cell-activating factor receptor antibody; BAFF R antibody; BAFF receptor antibody; BAFF-R antibody; BAFFR antibody; BLyS receptor 3 antibody; BlySR3 antibody; BR 3 antibody; BR3 antibody; BROMIX antibody; CD 268 antibody; CD268 antibody; CD268 antigen antibody; CVID4 antibody; MGC138235 antibody; OTTHUMP00000028746 antibody; Prolixin antibody; TNFRSF 13C antibody; Tnfrsf13c antibody; TR13C_HUMAN antibody; Tumor necrosis factor receptor subunit member 13C antibody; Tumor necrosis factor receptor superfamily member 13C antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Tumor necrosis factor receptor superfamily member 13C protein (1-78AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,TNFRSF13C Antibody (CSB-PA853495LA01HU),的標記方式是Non-conjugated。對于TNFRSF13C Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA853495LB01HU TNFRSF13C Antibody, HRP conjugated ELISA
    FITC CSB-PA853495LC01HU TNFRSF13C Antibody, FITC conjugated
    Biotin CSB-PA853495LD01HU TNFRSF13C Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
  • 基因功能參考文獻:
    1. the B-cell receptor BR3 modulates cellular branching via Rac1 during neuronal migration PMID: 27436754
    2. Expression patterns of BAFF and its receptor BAFF-R differ according to lupus nephritis class. PMID: 29087261
    3. up-regulated expression in intractable temporal lobe epilepsy PMID: 28441631
    4. Inhibition of ADAM10 augments BAFF-dependent survival of primary human B cells, whereas inhibition of ADAM17 increases BAFFR expression levels. PMID: 28249164
    5. Relationships between serum BAFF and BBR expression [(BAFFR, calcium signal modulating cyclophilic ligand interactor (TACI) and B cell maturation antigen (BCMA)] were determined on B cell subsets, defined using immunoglobulin (Ig)D/CD38. Twenty pre-RTX and 18 rheumatoid arthritis patients relapsing after B cell depletion were included. PMID: 28800164
    6. Among the BAFF receptors in a cohort of rheumatoid arthritis (RA) patients, the AA have shown, by fluorescence activated cell sorter (FACS) analysis of median fluorescence intensity (MFI), that transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) and B cell maturation antigen (BCMA) do not change PMID: 28834574
    7. The expression levels of serum BAFF and the three receptors (TACI, BCMA and BAFF-R) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls. PMID: 28028945
    8. Variants in BAFF-R gene is associated with chronic lymphocytic leukemia. PMID: 27468724
    9. BAFF-R, as the principal receptor of BAFF, not only decreased the apoptosis of B cells and CD8+ T cells by upregulating the expression of Bcl-2 and BclxL, but also promoted B-cell proliferation in immune thrombocytopenia. PMID: 26749059
    10. genetic polymorphism contributes to the pathogenesis of primary antibody deficiency PMID: 26613719
    11. BAFF and BAFF-R are expressed in the thyrocytes derived from patients with either autoimmune thyroid disorders or multinodular goiter, as well in the infiltrating immune cells of Graves' disease and Hashimoto's thyroiditis PMID: 26214745
    12. There is an increased prevalence of the BAFF-R His159Tyr mutation in patients with Sjogren's syndrome (SS), particularly in those with SS complicated by MALT lymphoma whose disease onset occurred at a younger age. PMID: 26097183
    13. Expression of mutant caspase-9 correlated with a downregulation of BAFFR (B-cell-activating factor belonging to the TNF family (BAFF) receptor) in B cells and ICOS (inducible T-cell costimulator) in T cells. PMID: 25569260
    14. Variants of TNFRSF13C were associated with common variable immunodeficiency. PMID: 26122175
    15. Negative expression of BAFF-R, but not of BAFF, could be an independent risk factor for progression-free survival and Overall survival in patients with diffuse large B-cell lymphoma treated with standard R-CHOP. PMID: 26327569
    16. the common TLR4-D299G, TLR4-T399I and BAFFR-P21R polymorphisms provide the carriers with a protective advantage against ICU-acquired sepsis; this finding was more profound for medical patients compared to trauma or surgical ones PMID: 25454804
    17. Data show significant differences in expression of tumour necrosis factor family (BAFF) receptors BAFF-R, BCMA and TACI in patients with and without anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies. PMID: 25301447
    18. In view of the restricted expression of the BAFF-R on normal cells and the multiple anti-pre-B ALL activities stimulated by this antibody, a further examination of its use for treatment of pre-B ALL is warranted. PMID: 24825858
    19. Availability of BAFF determines BAFF-R and TACI expression on B cells in common variable immunodeficiency. PMID: 24809296
    20. Our study demonstrates that BR3 is involved in the survival of cultured epithelial cells due to an autocrine effect of BAFF. PMID: 24602383
    21. BAFF-R, but not BAFF, may have a role in progression-free survival and overall survival in follicular lymphoma PMID: 23272079
    22. BLyS and its receptors are expressed by B lymphocytes in the peripheral blood and the bone marrow of patients with multiple myeloma. PMID: 23276925
    23. P21R/H159Y TNFRSF13C compound heterozygous mutation and P21R heterozygous mutations were detected in Turkish patients with common variable immunodeficiency. PMID: 22699762
    24. BAFF-R expression is tightly regulated during B-cell development in mouse and human and this exprssion is correlated with posirive selection. PMID: 22028296
    25. It was also found that NF-kappaB was an important transcription factor involved in regulating BAFF-R expression through one NF-kappaB binding site in the BAFF-R promoter PMID: 21607696
    26. Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors. PMID: 22124120
    27. The activation profile of diffuse large B-cell lymphomas/posttransplantation lymphoproliferative disorders was not associated with BAFF/BAFF-R expression, whereas nuclear p52 activation might be linked to Epstein-Barr virus. PMID: 21871426
    28. The human BAFF-R gene might be regulated via a transcriptional event through one putative NF-kappaB site on the BAFF-R gene promoter. PMID: 21744373
    29. reduced expression via inhibition of the NF-KappaB pathway in B cells of rheumatoid arthritis patients PMID: 21515993
    30. primary leukemia B-cell precursors aberrantly express receptors of the BAFF-system, BAFF-R, BCMA, and TACI PMID: 21687682
    31. This is the first study, presenting together the TNFSF members APRIL, BAFF, TWEAK and their receptors in different areas of normal renal tissue and renal cell carcinoma. PMID: 21483105
    32. BLyS and its receptors might have a potential role in the growth and survival of malignant plasma cells. PMID: 19731825
    33. Results describe the mechanisms underlying aberrant BAFF-R expression in precursor B acute lymphoblastic leukemia (precursor B-ALL) and mature B chronic lymphocytic leukemia (CLL). PMID: 21099364
    34. BAFF-R was rather specifically related to low growth activity of germinal center B-cell-like -type diffuse large B-cell lymphoma of nodal origin. PMID: 21123970
    35. inverse correlation between BAFF and APRIL in Kawasaki disease is reversed by IVIG treatment PMID: 20945608
    36. Elevated plasma BAFF and reduced BAFF receptor 3 (BR3) protein expression on peripheral B cells could act as biomarkers for active disease in systemic lupus erythematosus patients PMID: 20974656
    37. a novel lymphoma-associated mutation in human BAFF-R that results in NF-kappaB activation and reveals TRAF6 as a necessary component of normal BAFF-R signaling. PMID: 21041452
    38. Data from BAFF-R-expressing cells suggested potential regulatory sites in TNFRSF13C promoter region. PMID: 20554963
    39. This report is the first showing universal expression of BAFF-R by pre-B ALL cells. PMID: 20460528
    40. IFN-gamma and the NF-kappaB pathway could be involved in regulating the transcription and mRNA expression of BAFF-R gene. PMID: 20230666
    41. the mechanism of transcriptional regulation of BAFF-R PMID: 20025535
    42. BAFF-R is a receptor for the TNF family member ligand, BAFF [review] PMID: 12456020
    43. BAFFR-mediated NF-kappa B activation and IL-10 production in B cells is downregulated by TNFR-associated factor-3. PMID: 12471121
    44. crystal structure and interaction with BAFF protein PMID: 12715002
    45. BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site. PMID: 12755599
    46. Expression of BCMA, TACI, and BAFF-R by multiple myeloma cells support cell growth and survival. PMID: 14512299
    47. This study reports the crystal structure of a 24-residue fragment of the cytoplasmic portion of BAFF-R bound in complex with TRAF3. PMID: 15585864
    48. the PVPAT sequence of BAFFR not only functions as a key signaling motif of BAFFR but also determines its signaling specificity in the induction of the noncanonical NF-kappaB pathway PMID: 15644327
    49. amino acid sequence of genomic DNA from blood of common variable immunodeficiency patients;mutations may result in humoral immunodeficiency PMID: 16160919
    50. BAFF-R is expressed on most mature B cells and B-cell lymphoproliferative disorders. PMID: 16226112

    顯示更多

    收起更多

  • 相關疾病:
    Immunodeficiency, common variable, 4 (CVID4)
  • 亞細胞定位:
    Membrane; Single-pass type III membrane protein.
  • 組織特異性:
    Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
  • 數據庫鏈接:

    HGNC: 17755

    OMIM: 606269

    KEGG: hsa:115650

    STRING: 9606.ENSP00000291232

    UniGene: Hs.344088



主站蜘蛛池模板: 亚洲色大18成人网站www在线播放| 国产999精品成人网站| 豆国产96在线 | 亚洲| 亚洲中文久久精品无码照片 | 日韩国产精品人妻无码久久久| 久久国内精品自在自线400部 | 亚洲大色堂人在线无码| 熟妇人妻激情偷爽文| 国产又大又硬又粗| 精品国产黑色丝袜高跟鞋| 人妻熟女av一区二区三区| 久青草国产97香蕉在线视频| 蜜桃视频在线观看免费视频网站www| 爆乳熟妇一区二区三区| 国产高潮又爽又刺激的视频| 国产99在线 | 中国| 国产精品久久一区二区三区| 久久久无码人妻精品无码| 国产精品国产三级国产剧情| 又色又爽又黄高潮的免费视频| 揄拍成人国产精品视频| 免费无码不卡中文字幕在线| 亚洲精品午夜一区人人爽| 亚洲国产成人久久综合| 牛和人交xxxx欧美| 日本中文字幕一区二区有码在线 | 激情爆乳一区二区三区| 天堂中文最新版在线中文| 亚洲va在线va天堂xx xx| 骚动漫十八禁在线观看| 女女互磨互喷水高潮les呻吟 | 在线亚洲综合欧美网站首页| 免费乱理伦片在线观看| 欧美最新精品videossexohd| 中文字幕人成乱码熟女免费 | 免费天堂无码人妻成人av电影| 亚洲色婷婷久久精品av蜜桃久久| 久久久噜噜噜久噜久久| 日本高清www无色夜在线视频| 免费无码一区二区三区a片百度| 女人色极品影院|