在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNFAIP8L3 Antibody

TNFAIP8L3 Antibody

  • 中文名稱：
    TNFAIP8L3兔多克隆抗體
  • 貨號：
    CSB-PA115238
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 1,293T 2,mouse-brain cells using primary antibody diluted at 1:1000(4°C overnight). Secondary antibody:Goat Anti-rabbit IgG IRDye 800( diluted at 1:5000, 25°C, 1 hour)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TNFAIP8L3
  • 別名：
    TNFAIP8L3 antibody; TIPE3 antibody; Tumor necrosis factor alpha-induced protein 8-like protein 3 antibody; TNF alpha-induced protein 8-like protein 3 antibody; TNFAIP8-like protein 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from Human TNFAIP8L3. at AA range: 15-45
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB,ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:10000-20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
  • 基因功能參考文獻：
    1. In addition to replicating a previously identified genome-wide significant locus for corneal astigmatism near the PDGFRA gene, gene-based analysis identified three novel candidate genes, CLDN7, ACP2, and TNFAIP8L3, that warrant further investigation to understand their role in the pathogenesis of corneal astigmatism. (Meta-analysis) PMID: 29422769
    2. TIPE3 downregulation correlates with its CpG island hypermethylation in several solid cancers. TIPE3 acts as a tumor suppressor in nasopharyngeal carcinoma (NPC), providing a further insight into NPC progression and representing a potential prognostic biomarker for NPC PMID: 30217224
    3. High TIPE3 expression in the plasma membrane is associated with non-small-cell lung cancer. PMID: 29510688
    4. TIPE3 protein was upregulated in breast cancer tissues and positively correlated to invasion and metastasis of human breast cancer cells by activating AKT and NF-kappaB signaling pathways. PMID: 28388580
    5. Further MD simulations confirmed the dynamic stability of these lipids in the TH domain. This computational analysis thus provides insight into the binding mode of phospholipids in the TH domain of the TIPE family of proteins. PMID: 27783229
    6. TIPE3 protein is highly expressed in most human carcinoma cell lines. These results suggest that TIPE3 may play important roles in carcinogenesis and cell secretion. PMID: 25479791
    7. human cancers have markedly upregulated TIPE3 expression. Knocking out TIPE3 diminishes tumorigenesis, whereas enforced TIPE3 expression enhances it in vivo PMID: 25242044

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell membrane.
  • 蛋白家族：
    TNFAIP8 family
  • 組織特異性：
    Widely expressed (at protein level). Highly expressed in most carcinoma cell lines.
  • 數據庫鏈接：

    HGNC: 20620

    OMIM: 616438

    KEGG: hsa:388121

    UniGene: Hs.306343



主站蜘蛛池模板： 人人做人人爽国产视| 又爽又黄又无遮挡的视频| 国产乱视频在线观看| 精品国产美女av久久久久| 亚洲欧美国产国产一区二区三区| 亚洲综合伊人久久大杳蕉| 扒开双腿疯狂进出爽爽爽| 久在线精品视频线观看| 亚洲欧美人成网站在线观看看| 久久九九国产精品怡红院| 欧美伊人久久大香线蕉综合| 亚洲第一成人网站在线播放| 全球成人中文在线| 欧美白丰满老太aaa片| 欧美性白人极品hd| 色与欲影视天天看综合网| 无码中字出轨中文人妻中文中 | 国产免费又爽又色又粗视频| 久久九九久精品国产日韩经典| 秋霞无码久久久精品交换| 国产成人一区二区不卡免费视频| 国内精品伊人久久久久影院麻豆 | 欧美激情猛片xxxⅹ大3| 午夜福利日本一区二区无码| 欧美三根一起进三p| 人妻洗澡被强公日日澡电影| 成 人 网 站94免费观看| 欧美交换国产一区内射| 亚洲色欲一区二区三区在线观看| 国产精品自产拍在线18禁| 成 人 黄 色 大片| 国产亚洲精品a久久777777| 色www视频永久免费| 在线中文新版最新版在线| 国产一区二区不卡在线看| 欧美人和黑人牲交网站上线| 日韩丰满少妇无吗视频激情内射 | 国产成人午夜精华液| 又污又爽又黄的网站| 亚洲乱码日产精品bd| 柠檬福利第一导航在线|