在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TNFAIP1 Antibody

  • 中文名稱:
    TNFAIP1兔多克隆抗體
  • 貨號:
    CSB-PA023956GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TNFAIP1
  • 別名:
    TNFAIP1 antibody; BACURD2 antibody; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody; hBACURD2 antibody; BTB/POZ domain-containing protein TNFAIP1 antibody; Protein B12 antibody; Tumor necrosis factor antibody; alpha-induced protein 1 antibody; endothelial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TNFAIP1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
  • 基因功能參考文獻:
    1. TNFAIP1 silence significantly increased the migrated and invaded cells compared to that in control, while these increases were abolished by miR-424 suppression. PMID: 28535539
    2. CREB is a negative regulator of the TNFAIP1 gene. PMID: 26398148
    3. TNFAIP1 plays an important role in mediating miR-15a dependent biological functions in osteosarcoma. PMID: 26261520
    4. MiR-181a played a critical role in regulating pancreatic cancer growth and migration, likely interacting with TNFAIP1. PMID: 26152285
    5. Results showed that the expression of TNFAIP1 protein was significantly increased in osteosarcoma tissues and associated with distant metastasis. PMID: 24969828
    6. Expression of TNFAIP1 is regulated by the transcriptional factor Sp1. PMID: 23912453
    7. TNFAIP1 inhibited the transcriptional activities of nuclear factor kappa B (NF-kappaB) and activating protein-1 reporters PMID: 22810651
    8. CK2 could phosphorylate TNFAIP1 in vitro and in vivo, which facilitated the distribution of TNFAIP1 in nucleus and enhanced its interaction with PCNA. PMID: 19851886
    9. The promoter region of human TNFAIP1 gene was functionally characterized. PMID: 19593659
    10. suggest that the TNFAIP1/POLDIP2 complex sense-antisense architecture represents a clinically significant transcriptional structural-functional gene module associated with amplification of the genomic region on 17q11.2 in breast cancer. PMID: 20158880
    11. TNFAIP1 shows increased transcript levels in Alzheimer's disease brains PMID: 12600716
    12. Expression levels of TNFAIP1 are high in COS7 and NIH3T3 cell lines but low in the cancer cell lines. PMID: 16870576

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.
  • 蛋白家族:
    BACURD family
  • 數據庫鏈接:

    HGNC: 11894

    OMIM: 191161

    KEGG: hsa:7126

    STRING: 9606.ENSP00000226225

    UniGene: Hs.76090



主站蜘蛛池模板: 国产精品亚洲a∨天堂| 国产真实野战在线视频| 久久亚洲中文无码咪咪爱| 国产精品禁18久久久夂久 | 伊人色综合久久天天| 麻豆视传媒精品av| 亚洲性夜色噜噜噜在线观看不卡| 女人被强╳到高潮喷水在线观看| 天堂一区人妻无码| 国产精品无码一区二区在线a片 | 国产精品丝袜高跟鞋| ww国产内射精品后入国产| 中文字幕人妻被公上司喝醉在线| 亚洲精品四区麻豆文化传媒| 国产又黄又爽又色的免费视频 | 丰满多毛的陰户视频| 日韩 亚洲 欧美 国产 精品| 亚洲第一无码精品立川理惠| 国产喷水福利在线视频| 337p日本欧洲亚洲大胆艺术图| 国产高清在线精品二区| av无码精品一区二区三区宅噜噜| 欧美xxxx做受欧美1314| 色五月丁香五月综合五月| 内射少妇一区27p| 日躁夜躁狠狠躁2001| 亚洲成在人线在线播放无码vr| 手机国产乱子伦精品视频| 国产一区二区| 狠狠色狠狠人格综合| 日本动漫瀑乳h动漫啪啪免费| 亚洲午夜未满十八勿入网站| 高潮喷水无码av亚洲| 在线观看国产精品乱码app| а天堂中文最新一区二区三区| 亚洲成熟女人毛毛耸耸多| 久久綾合久久鬼色88| 少妇又色又紧又爽又刺激视频| 免费大黄网站在线观| 婷婷五月深爱综合开心网| av制服丝袜白丝国产网站|