在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNFAIP1 Antibody

TNFAIP1 Antibody

  • 中文名稱：
    TNFAIP1兔多克隆抗體
  • 貨號：
    CSB-PA454097
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA454097(TNFAIP1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA454097(TNFAIP1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Lo2 and huvec cell, Primary antibody: CSB-PA454097(TNFAIP1 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TNFAIP1
  • 別名：
    TNFAIP1 antibody; BACURD2 antibody; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody; hBACURD2 antibody; BTB/POZ domain-containing protein TNFAIP1 antibody; Protein B12 antibody; Tumor necrosis factor antibody; alpha-induced protein 1 antibody; endothelial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TNFAIP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
  • 基因功能參考文獻：
    1. TNFAIP1 silence significantly increased the migrated and invaded cells compared to that in control, while these increases were abolished by miR-424 suppression. PMID: 28535539
    2. CREB is a negative regulator of the TNFAIP1 gene. PMID: 26398148
    3. TNFAIP1 plays an important role in mediating miR-15a dependent biological functions in osteosarcoma. PMID: 26261520
    4. MiR-181a played a critical role in regulating pancreatic cancer growth and migration, likely interacting with TNFAIP1. PMID: 26152285
    5. Results showed that the expression of TNFAIP1 protein was significantly increased in osteosarcoma tissues and associated with distant metastasis. PMID: 24969828
    6. Expression of TNFAIP1 is regulated by the transcriptional factor Sp1. PMID: 23912453
    7. TNFAIP1 inhibited the transcriptional activities of nuclear factor kappa B (NF-kappaB) and activating protein-1 reporters PMID: 22810651
    8. CK2 could phosphorylate TNFAIP1 in vitro and in vivo, which facilitated the distribution of TNFAIP1 in nucleus and enhanced its interaction with PCNA. PMID: 19851886
    9. The promoter region of human TNFAIP1 gene was functionally characterized. PMID: 19593659
    10. suggest that the TNFAIP1/POLDIP2 complex sense-antisense architecture represents a clinically significant transcriptional structural-functional gene module associated with amplification of the genomic region on 17q11.2 in breast cancer. PMID: 20158880
    11. TNFAIP1 shows increased transcript levels in Alzheimer's disease brains PMID: 12600716
    12. Expression levels of TNFAIP1 are high in COS7 and NIH3T3 cell lines but low in the cancer cell lines. PMID: 16870576

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.
  • 蛋白家族：
    BACURD family
  • 數據庫鏈接：

    HGNC: 11894

    OMIM: 191161

    KEGG: hsa:7126

    STRING: 9606.ENSP00000226225

    UniGene: Hs.76090



主站蜘蛛池模板： 人人澡人人曰人人摸看| 无尺码精品产品视频| 国产免费麻传媒精品国产av| 99精品国产再热久久无毒不卡 | 仙踪林果冻传媒一区二区| 久久人人超碰精品caoporen| 国产成人愉拍精品| 秋霞午夜成人久久电影网| 99国产精品久久久蜜芽| 少妇扒开双腿让我看个够| 妲己丰满人熟妇大尺度人体艺| 午夜羞羞影院男女爽爽爽| 我和亲妺妺乱的性视频| 美女把尿囗扒开让男人添| 92国产精品午夜福利无毒不卡 | 亚洲精品午夜一区二区电影院| 18女下面流水不遮图| 中国无码人妻丰满熟妇啪啪软件| 国产suv精品一区二区883| 日本妇人成熟免费中文字幕| 久久久久国色av免费观看| 久久精品国产色蜜蜜麻豆| 欧美精品18videosex性欧美| 亚洲国产成人精品无码一区二区| 亚洲色爱图小说专区| 天天摸日日摸狠狠添| 久久香蕉国产线看观看怡红院妓院 | 欧美成人看片一区二三区图文| 国产女主播白浆在线看| 亚洲国产精品综合久久20| 娇妻被黑人粗大高潮白浆| 成人免费午夜无码视频在线播放| 国精产品48x国精产品| 国产精品宾馆在线精品酒店| 三级视频兔费看| 国产亚洲精品福利视频在线观看| 国产av一区二区精品久久| 国产日韩精品中文字无码| 欧美大屁股流白浆xxxx| 天天躁夜夜躁狠狠综合| 人妻巨大乳一二三区|