在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TNFAIP1 Antibody

TNFAIP1 Antibody

  • 中文名稱：
    TNFAIP1兔多克隆抗體
  • 貨號：
    CSB-PA454097
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA454097(TNFAIP1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA454097(TNFAIP1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Lo2 and huvec cell, Primary antibody: CSB-PA454097(TNFAIP1 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TNFAIP1
  • 別名：
    TNFAIP1 antibody; BACURD2 antibody; EDP1BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 antibody; hBACURD2 antibody; BTB/POZ domain-containing protein TNFAIP1 antibody; Protein B12 antibody; Tumor necrosis factor antibody; alpha-induced protein 1 antibody; endothelial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human TNFAIP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
  • 基因功能參考文獻：
    1. TNFAIP1 silence significantly increased the migrated and invaded cells compared to that in control, while these increases were abolished by miR-424 suppression. PMID: 28535539
    2. CREB is a negative regulator of the TNFAIP1 gene. PMID: 26398148
    3. TNFAIP1 plays an important role in mediating miR-15a dependent biological functions in osteosarcoma. PMID: 26261520
    4. MiR-181a played a critical role in regulating pancreatic cancer growth and migration, likely interacting with TNFAIP1. PMID: 26152285
    5. Results showed that the expression of TNFAIP1 protein was significantly increased in osteosarcoma tissues and associated with distant metastasis. PMID: 24969828
    6. Expression of TNFAIP1 is regulated by the transcriptional factor Sp1. PMID: 23912453
    7. TNFAIP1 inhibited the transcriptional activities of nuclear factor kappa B (NF-kappaB) and activating protein-1 reporters PMID: 22810651
    8. CK2 could phosphorylate TNFAIP1 in vitro and in vivo, which facilitated the distribution of TNFAIP1 in nucleus and enhanced its interaction with PCNA. PMID: 19851886
    9. The promoter region of human TNFAIP1 gene was functionally characterized. PMID: 19593659
    10. suggest that the TNFAIP1/POLDIP2 complex sense-antisense architecture represents a clinically significant transcriptional structural-functional gene module associated with amplification of the genomic region on 17q11.2 in breast cancer. PMID: 20158880
    11. TNFAIP1 shows increased transcript levels in Alzheimer's disease brains PMID: 12600716
    12. Expression levels of TNFAIP1 are high in COS7 and NIH3T3 cell lines but low in the cancer cell lines. PMID: 16870576

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes.
  • 蛋白家族：
    BACURD family
  • 數據庫鏈接：

    HGNC: 11894

    OMIM: 191161

    KEGG: hsa:7126

    STRING: 9606.ENSP00000226225

    UniGene: Hs.76090



主站蜘蛛池模板： 夜夜躁狠狠躁日日躁| 亚洲性夜色噜噜噜在线观看不卡| 亚洲成av人片天堂网| 日日碰狠狠添天天爽| 伊人色综合久久天天小片| 无码国内精品久久人妻蜜桃| 在线观看精品视频网站| 毛片免费视频| 解开人妻的裙子猛烈进入| 青青草无码伊人久久| 免费啪视频在线观看视频网页| 欧美xxxxx精品| 18禁裸乳无遮挡啪啪无码免费| 无码av动漫精品一区二区免费| 精品无码久久久久久尤物| 成熟女人牲交片免费观看视频| 老太脱裤子让老头玩xxxxx| 人妻avav中文系列久久| 久久精品人人做人人综合| 亚洲乱妇老熟女爽到高潮的片| 无码色偷偷亚洲国内自拍| 狠狠色老熟妇老熟女| 蜜桃av噜噜一区二区三区| 3d动漫精品啪啪一区二区免费| 国产一区二区三区免费高清在线播放| 成人av片在线观看免费| 暖暖视频日本| 欧美成人家庭影院| 无码动漫性爽xo视频在线观看| 日亚韩在线无码一区二区三区| 亚洲 欧美 国产 日韩 中文字幕| 日本成本人片视频免费| 人妻无码手机在线中文| 最爽爱爱高潮免费视频| 国偷自产一区二区免费视频| 国产精品久久自在自线不卡| 欧洲精品成人免费视频在线观看 | 蜜臀av无码人妻精品| 无码av最新无码av专区| 国产制服日韩丝袜86页| 中文字幕人妻无码系列第三区|