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  4. TMTC1 Antibody, Biotin conjugated

TMTC1 Antibody, Biotin conjugated

  • 中文名稱：
    TMTC1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA808537LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TMTC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMTC1
  • 別名：
    TMTC1 antibody; ARG99 antibody; Protein O-mannosyl-transferase TMTC1 antibody; EC 2.4.1.109 antibody; Transmembrane and TPR repeat-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane and TPR repeat-containing protein 1 protein (1-227AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3.
  • 基因功能參考文獻(xiàn)：
    1. O-mannosylation pathway dedicated to cadherins/ protocadherins orchestrated by the four TMTC1-4 genes PMID: 28973932
    2. findings provide an important link between aneuploidy and the stress pathways activated by Aurora B inhibition and also support the use of Aurora B inhibitors in combination therapy for treatment of cancer. PMID: 24764305
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
  • 蛋白家族：
    TMTC family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24099

    OMIM: 615855

    KEGG: hsa:83857

    STRING: 9606.ENSP00000442046

    UniGene: Hs.401954



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