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TMIGD2 Antibody, FITC conjugated

  • 中文名稱：
    TMIGD2兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA850263LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TMIGD2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CD28H antibody; IGPR 1 antibody; IGPR1 antibody; immunoglobulin and proline-rich receptor 1 antibody; immunoglobulin-containing and proline-rich receptor 1 antibody; TMIG2_HUMAN antibody; TMIGD2 antibody; Transmembrane and immunoglobulin domain containing 2 antibody; Transmembrane and immunoglobulin domain-containing protein 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 2 antibody; transmembrane and immunoglobulin domain-containing protein 2 variant 3 antibody; UNQ3059/PRO9879 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane and immunoglobulin domain-containing protein 2 protein (23-150AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
  • 基因功能參考文獻(xiàn)：
    1. The authors demonstrate that IGPR-1 is localized to endothelial adherens junctions and, through trans-homophilic dimerization, regulates endothelial cell-cell adhesion and barrier function. PMID: 27838321
    2. B7 homologue 5 (B7-H5), was identified as a specific ligand for CD28H. PMID: 23784006
    3. Authors identified IGPR-1, also called TMIGD2, gene as a novel cell adhesion receptor that is expressed in various human organs and tissues, mainly in cells with epithelium and endothelium origins. PMID: 22419821
  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性：
    Widely expressed, mainly by epithelial and endothelial cells, including bronchial epithelial cells of lung, breast glandular and lobular epithelia cells, urothelium of the bladder, skin epidermis, epithelium of gastrointestinal, rectum, endometrial glands
  • 數(shù)據(jù)庫鏈接：

    HGNC: 28324

    OMIM: 614715

    KEGG: hsa:126259

    UniGene: Hs.263928



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