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  4. TMEM47 Antibody, Biotin conjugated

TMEM47 Antibody, Biotin conjugated

  • 中文名稱：
    TMEM47兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA023845LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TMEM47 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TMEM47
  • 別名：
    TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transmembrane protein 47 protein (42-82AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin.
  • 基因功能參考文獻：
    1. TM4SF10, possibly through ADAP, may regulate Fyn activity PMID: 21881001
    2. Single nucleotide polymorphisms, but no disease-associated mutations, were identified in X-linked mental retardation patients. PMID: 15345028
    3. A 4-transmembrane protein, related to PMP22/EMPs and the Claudins, localizes to the plasma membrane and the ER. The mRNA is present in high amounts in brain. PMID: 11472633
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
  • 蛋白家族：
    TMEM47 family
  • 組織特異性：
    Expressed in adult brain, fetal brain, cerebellum, heart, lung, prostate and thyroid.
  • 數據庫鏈接：

    HGNC: 18515

    OMIM: 300698

    KEGG: hsa:83604

    UniGene: Hs.8769



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