在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TMEM175 Antibody

TMEM175 Antibody

  • 中文名稱：
    TMEM175兔多克隆抗體
  • 貨號(hào)：
    CSB-PA023756GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TMEM175
  • 別名：
    TMEM175 antibody; Endosomal/lysosomal potassium channel TMEM175 antibody; Transmembrane protein 175 antibody; hTMEM175 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TMEM175
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel. Constitutes the pore-forming subunit of the lysoK(GF) complex, a complex activated by extracellular growth factors. The lysoK(GF) complex is composed of TMEM175 and AKT (AKT1, AKT2 or AKT3), a major target of growth factor receptors: in the complex, TMEM175 channel is opened by conformational changes by AKT, leading to its activation. The lysoK(GF) complex is required to protect neurons against stress-induced damage.
  • 基因功能參考文獻(xiàn)：
    1. TMEM175 deficiency impairs lysosomal and mitochondrial function and increases alpha-synuclein aggregation. PMID: 28193887
    2. structure of TMEM175 represents a novel architecture of a tetrameric cation channel whose ion selectivity mechanism appears to be distinct from that of the classical K(+) channel family PMID: 28723891
    3. Data indicated that GBA and TMEM175/GAK significantly alter age at onset in PD. PMID: 25914293
  • 相關(guān)疾病：
    Parkinson disease (PARK)
  • 亞細(xì)胞定位：
    Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    TMEM175 family
  • 組織特異性：
    Widely expressed.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 28709

    OMIM: 168600

    KEGG: hsa:84286

    UniGene: Hs.478936



主站蜘蛛池模板： 亚洲中文字幕人成乱码| 日韩激情无码免费毛片| 97久久精品人人做人人爽| 久久人妻天天av| 午夜精品久久久久久久久久久久| 久久精品国产久精国产一老狼| 精品国产乱码久久久久久下载| 天堂资源在线www在线观看| 精品人妻va出轨中文字幕| 18禁成人网站免费观看| 综合图片亚洲综合网站| 中文字幕无码av正片| 亚洲色中文字幕在线播放| 欧美人与性动交α欧美精品 | 中文字幕人妻丝袜成熟乱| 亚洲毛片αv无线播放一区| 国产麻豆剧传媒精品av| 最新69国产成人精品视频免费| 欧美日韩国产亚洲沙发| 再深点灬舒服灬太大了在线视频| 人妻av中文字幕久久| 国内精品伊人久久久久777| 免费国产h视频在线观看| 超碰97人人让你爽| 亚洲乱码av中文一区二区| 毛茸茸性xxxx毛茸茸毛茸茸| 女乱高潮久久久久久爽爽| 欧美成人高清视频a在线看| 嫩草av久久伊人妇女超级a| 色欲久久久天天天综合网精品| 爽爽午夜影视窝窝看片| 精品国产免费人成电影在线看| 午夜成人理论无码电影在线播放 | 疯狂撞击丝袜人妻| 精品亚洲一区二区三区在线播放 | 亚洲性人人天天夜夜摸18禁止| 亚洲综合久久一本久道| 我和亲妺妺乱的性视频| 综合激情久久综合激情| 国产av天堂亚洲国产av麻豆| 欧美老熟妇videos极品另类|