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TMEM14A Antibody, FITC conjugated

  • 中文名稱:
    TMEM14A兔多克隆抗體, FITC偶聯(lián)
  • 貨號:
    CSB-PA023720LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TMEM14A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMEM14A
  • 別名:
    TMEM14A; C6orf73; PTD011; Transmembrane protein 14A
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Transmembrane protein 14A protein (45-78AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Inhibits apoptosis via negative regulation of the mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
  • 基因功能參考文獻(xiàn):
    1. these results indicate that TMEM14A has a pro-tumorigenic effect in ovarian cancer cells, suggesting an important role of this protein in ovarian cancer oncogenesis and metastasis. PMID: 26896463
    2. findings show for the first time that TMEM14A inhibits apoptosis by blocking the mitochondrial permeability transition and stabilizing mitochondrial membrane potential PMID: 21723035
  • 亞細(xì)胞定位:
    Mitochondrion membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane.
  • 蛋白家族:
    TMEM14 family
  • 組織特異性:
    Expressed at significantly higher levels in ovarian cancer tissues than in normal tissues (at protein level).
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21076

    KEGG: hsa:28978

    UniGene: Hs.94896



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