在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TMBIM4 Antibody

  • 中文名稱:
    TMBIM4兔多克隆抗體
  • 貨號:
    CSB-PA030016
  • 規格:
    ¥1090
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TMBIM4
  • 別名:
    TMBIM4; GAAP; LFG4; CGI-119; Protein lifeguard 4; Golgi anti-apoptotic protein; Protein S1R; Transmembrane BAX inhibitor motif-containing protein 4; Z-protein
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human GAAP.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.
  • 基因功能參考文獻:
    1. Residues contributing to the ion-conducting pore have been defined and provide the first clues about the mechanistic link between these very different functions of golgi anti-apoptotic protein (GAAP) [review]. PMID: 28469007
    2. The hGAAP is a novel regulator of focal adhesion dynamics, cell adhesion, and migration by controlling localized Ca(2+)-dependent activation of calpain. PMID: 23940116
    3. GAAP can oligomerize in a pH-regulated manner, and monomeric GAAP is functional. PMID: 23508950
    4. Taken together, the proposed interaction between Chlamydia pneumoniae protein CPn0809 and GAAP modulates bacterial growth in A549 cells. PMID: 23000903
    5. Data indicate that GAAP and BI-1 have a six membrane-spanning topology with cytosolic N and C termini and a C-terminal reentrant loop. PMID: 22418439
    6. Stable expression of both viral GAAP (v-GAAP) and human GAAP (h-GAAP), which is expressed in all human tissues tested, inhibited apoptosis induced by intrinsic and extrinsic apoptotic stimuli PMID: 17319741
    7. The tmbim4 may participate in cell death regulation by interacting with proteins of Bcl-2 family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments PMID: 18440869
    8. Data demonstrate that h-GAAP modulates intracellular Ca(2+) fluxes induced by both physiological and apoptotic stimuli. PMID: 19553469

    顯示更多

    收起更多

  • 亞細胞定位:
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族:
    BI1 family, LFG subfamily
  • 數據庫鏈接:

    HGNC: 24257

    KEGG: hsa:51643

    STRING: 9606.ENSP00000350965

    UniGene: Hs.505934



主站蜘蛛池模板: 亚洲成av人片在线观看| 99国产精品欧美一区二区三区 | 精品无码久久久久国产app| 影音先锋亚洲成aⅴ人在| 国产极品粉嫩福利姬萌白酱| 97久久精品亚洲中文字幕无码| 一本一道色欲综合网中文字幕| 亚洲 日韩 国产 中文有码| 护士张开腿被奷日出白浆| 免费无码黄十八禁网站在线观看 | 亚洲国产精品无码久久久久高潮| 午夜福利体验免费体验区| 免费无码午夜福利片69| 少妇人妻偷人激情视频| 女人大荫蒂毛茸茸视频| 香蕉免费一区二区三区在| 久久九九有精品国产23百花影院| 国产精品亚洲一区二区z| 亚洲性啪啪无码av天堂| 精品人妻中文字幕有码在线| 无遮无挡爽爽免费视频| 精品无码国模私拍视频| 久久久久黑人强伦姧人妻| 中文字幕一区二区人妻电影| 国产精品嫩草影院免费观看| 国产一区二区三区无码免费 | 国产9 9在线 | 中文| 日本午夜精品一区二区三区电影| 亚洲第一在线综合网站| 久久精品国产99精品国产亚洲性色| 福利视频在线播放| 青乐娱精品视频一国产分类| 久久综合av免费观看| 中文字幕乱码中文乱码777| 日产日韩亚洲欧美综合下载| 青青草免费国产线观720| 内射囯产旡码丰满少妇| 深夜国产一区二区三区在线看 | 一区二区视频日韩免费| 日韩欧美在线综合网另类| 无码人妻精品一区二区三区99不卡 |