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TMBIM1 Antibody

  • 中文名稱:
    TMBIM1兔多克隆抗體
  • 貨號:
    CSB-PA853376LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: TMBIM1 antibody at 8µg/ml
      Lane 1: U251 whole cell lysate
      Lane 2: K562 whole cell lysate
      Lane 3: A549 whole cell lysate
      Lane 4: MCF-7 whole cell lysate
      Lane 5: Mouse lung tissue
      Lane 6: Mouse liver tissue
      Lane 7: Mouse kidney tissue
      Lane 8: Human placenta tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 35 kDa
      Observed band size: 35 kDa
    • Immunofluorescent analysis of U251 cells using CSB-PA853376LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TMBIM1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TMBIM1
  • 別名:
    TMBIM1; LFG3; RECS1; PP1201; PSEC0158; Protein lifeguard 3; Protein RECS1 homolog; Transmembrane BAX inhibitor motif-containing protein 1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Protein lifeguard 3 protein (1-109AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,TMBIM1 Antibody (CSB-PA853376LA01HU),的標記方式是Non-conjugated。對于TMBIM1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA853376LB01HU TMBIM1 Antibody, HRP conjugated ELISA
    FITC CSB-PA853376LC01HU TMBIM1 Antibody, FITC conjugated
    Biotin CSB-PA853376LD01HU TMBIM1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
  • 基因功能參考文獻:
    1. The combined analysis identified a new risk association for colorectal cancer (CRC) at 2q35 marked by rs992157 which is intronic to PNKD and TMBIM1.Intriguingly this susceptibility single-nucleotide polymorphism (SNP) is in strong linkage disequilibrium (r(2) = 0.90, D' = 0.96) with the previously discovered GWAS SNP rs2382817 for inflammatory bowel disease (IBD). PMID: 27005424
    2. TMBIM1 is an effective suppressor of steatohepatitis and a previously unknown regulator of the multivesicular body (MVB)-lysosomal pathway. PMID: 28481357
    3. These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2) homeostasis in a wide variety of tissues PMID: 25764978
    4. data suggest that PP1201 functions as an anti-apoptotic protein and its increased expression in vascular cells can contribute to homeostasis by reducing Fas trafficking to the cell membrane PMID: 21107705
    5. The tmbim1 may participate in cell death regulation by interacting with proteins of Bcl-2 family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments PMID: 18440869

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  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
  • 蛋白家族:
    BI1 family, LFG subfamily
  • 數據庫鏈接:

    HGNC: 23410

    OMIM: 610364

    KEGG: hsa:64114

    STRING: 9606.ENSP00000258412

    UniGene: Hs.591605



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