在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TIMM50 Antibody

TIMM50 Antibody

  • 中文名稱：
    TIMM50兔多克隆抗體
  • 貨號：
    CSB-PA674736ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: TIMM50 antibody at 4.05µg/ml
      Lane 1: Rat heart tissue
      Lane 2: MM231 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: Hela whole cell lysate
      Lane 5: 293T whole cell lysate
      Lane 6: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40, 51, 28 kDa
      Observed band size: 40 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA674736ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA674736ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TIMM50 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TIMM50
  • 別名：
    TIMM50; TIM50; PRO1512; Mitochondrial import inner membrane translocase subunit TIM50
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Mitochondrial import inner membrane translocase subunit TIM50 protein (87-353AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.; May participate in the release of snRNPs and SMN from the Cajal body.
  • 基因功能參考文獻：
    1. Expression of TIM50 was downregulated in hypertrophic hearts. PMID: 28432072
    2. Missense mutations in TIMM50 are likely manifesting by severe intellectual disability and epilepsy accompanied by 3-methylglutaconic aciduria and variable mitochondrial complex V deficiency. PMID: 27573165
    3. TIM50 has a role in regulating cell proliferation and apoptosis through decreasing mitochondrial membrane potential in breast cancer cell PMID: 26289846
    4. the interaction of divalent metal ions with the intermembrane space domain of Tim50 (Tim50(IMS)) and the interaction of presequence peptides with Tim50(IMS) in presence of Ca(2+) ion was investigated. PMID: 23098911
    5. The far-UV CD spectra of Tim50(IMS) in native and denatured states revealed that the protein has a significantly folded secondary structure consisted of alpha-helixes and beta-sheets. PMID: 21742040
    6. Tim50 regulates 3betaHSD2 expression and activity, representing a new role for translocases in steroidogenesis. PMID: 21930695
    7. TIM50, was upregulated in a non-small cell lung carcinoma cell line (H1299) that expressed the p53 mutants R175H and R273H compared to cells lacking p53. PMID: 21621504
    8. Tim50 is important for both mitochondrial function and early neuronal development PMID: 15044455
    9. Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with coilin, snRNPs, and SMN PMID: 16008839

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.; [Isoform 2]: Nucleus speckle.
  • 蛋白家族：
    TIM50 family
  • 組織特異性：
    Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
  • 數據庫鏈接：

    HGNC: 23656

    OMIM: 607381

    KEGG: hsa:92609

    STRING: 9606.ENSP00000318115

    UniGene: Hs.590956



主站蜘蛛池模板： 国产一区二区在线视频| 久久九九兔免费精品6| 精品国产美女av久久久久| 美女扒开奶罩露出奶头视频网站 | 在线v片免费观看视频| 丰满少妇被猛烈进入av久久| 内射白嫩少妇超碰| 日韩精品无码一区二区三区久久久 | 久久久肥妇熟女ⅹxxx毛片| 国产成人无码av一区二区| 亚洲日韩欧洲乱码av夜夜摸| 俺也来俺也去俺也射| 久久综合一色综合久久小蛇| 久久综合久久自在自线精品自| 人人超碰人人超级碰国| 精品亚洲欧美无人区乱码| 国产一三四2021不卡| 内射人妻无套中出无码| av无码人妻一区二区三区牛牛| 国产亚洲999精品aa片在线爽 | 人人爽人人爱| 精品久久久久久久久久中文字幕| 国产精品理论片在线观看| 性色高清xxxxx厕所偷窥| 激情综合婷婷丁香五月蜜桃| 日韩av无码免费播放| 中文在线中文资源| 性色欲情网站| 777米奇色狠狠俺去啦| 在线看片福利无码网址| 99久久人妻精品免费二区| 国产精品无码专区久久久| 欧美人妻体内射射| 伊人久久大香线焦av综合影院| 久久久久久九九99精品| 国产未发育呦交视频| 性国产牲交xxxxx视频| 亚洲 欧洲 日韩 综合av| 国产白嫩美女在线观看| 疯狂做受xxxx高潮不断| 无码中字出轨中文人妻中文中 |