在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TIMM50 Antibody

TIMM50 Antibody

  • 中文名稱：
    TIMM50兔多克隆抗體
  • 貨號：
    CSB-PA674736ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: TIMM50 antibody at 4.05µg/ml
      Lane 1: Rat heart tissue
      Lane 2: MM231 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: Hela whole cell lysate
      Lane 5: 293T whole cell lysate
      Lane 6: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40, 51, 28 kDa
      Observed band size: 40 kDa
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA674736ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA674736ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TIMM50 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TIMM50
  • 別名：
    TIMM50; TIM50; PRO1512; Mitochondrial import inner membrane translocase subunit TIM50
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Mitochondrial import inner membrane translocase subunit TIM50 protein (87-353AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo.; May participate in the release of snRNPs and SMN from the Cajal body.
  • 基因功能參考文獻：
    1. Expression of TIM50 was downregulated in hypertrophic hearts. PMID: 28432072
    2. Missense mutations in TIMM50 are likely manifesting by severe intellectual disability and epilepsy accompanied by 3-methylglutaconic aciduria and variable mitochondrial complex V deficiency. PMID: 27573165
    3. TIM50 has a role in regulating cell proliferation and apoptosis through decreasing mitochondrial membrane potential in breast cancer cell PMID: 26289846
    4. the interaction of divalent metal ions with the intermembrane space domain of Tim50 (Tim50(IMS)) and the interaction of presequence peptides with Tim50(IMS) in presence of Ca(2+) ion was investigated. PMID: 23098911
    5. The far-UV CD spectra of Tim50(IMS) in native and denatured states revealed that the protein has a significantly folded secondary structure consisted of alpha-helixes and beta-sheets. PMID: 21742040
    6. Tim50 regulates 3betaHSD2 expression and activity, representing a new role for translocases in steroidogenesis. PMID: 21930695
    7. TIM50, was upregulated in a non-small cell lung carcinoma cell line (H1299) that expressed the p53 mutants R175H and R273H compared to cells lacking p53. PMID: 21621504
    8. Tim50 is important for both mitochondrial function and early neuronal development PMID: 15044455
    9. Tim50a, a nuclear isoform of the mitochondrial Tim50, interacts with coilin, snRNPs, and SMN PMID: 16008839

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.; [Isoform 2]: Nucleus speckle.
  • 蛋白家族：
    TIM50 family
  • 組織特異性：
    Widely expressed. Expressed at higher level in brain, kidney and liver (at protein level).
  • 數據庫鏈接：

    HGNC: 23656

    OMIM: 607381

    KEGG: hsa:92609

    STRING: 9606.ENSP00000318115

    UniGene: Hs.590956



主站蜘蛛池模板： 久热这里只有精品99| 欧美精品18videosex性欧美| 熟女熟妇伦av网站| 茄子在线看片免费人成视频| 国产裸体xxxx视频| 51精品国产人成在线观看| 韩国三级hd中文字幕| 国产成人av区一区二区三| 色偷偷一区二区无码视频| 麻豆高清免费国产一区| 熟妇人妻午夜寂寞影院| 成人午夜无码精品免费看| 在线|国产精品女主播阳台| 嫩草伊人久久精品少妇av| 精品少妇人妻av无码久久| 亚洲欧美韩国综合色| 亚洲最大无码av网站观看| 无码人妻丰满熟妇奶水区码| 无码人妻久久一区二区三区蜜桃 | 久久久久国色av免费看图片| 高清国产av一区二区三区| 国产真实夫妇视频| 亚洲v国产v欧美v久久久久久| 久久国产免费福利永久| 在线精品自偷自拍无码| 国产l精品国产亚洲区久久| 成 人 黄 色 大片| 一区二区三区在线 | 日| 亚洲精品国产suv| 中文韩国午夜理伦三级好看| 精品日韩亚洲欧美高清a| 狠狠色噜噜狠狠狠狠7777米奇| 国产亚洲一区二区在线观看| 久久www色情成人免费| 久久天天躁夜夜躁狠狠躁| 久久久久波多野结衣高潮| 无码人妻品一区二区三区精99| 亚洲国产精品成人影片久久| 精品1卡二卡三卡四卡老狼| 无码人妻精品一区二区三| 疯狂迎合进入强壮公的视频|