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TIMM44 Antibody

  • 中文名稱:
    TIMM44兔多克隆抗體
  • 貨號:
    CSB-PA023555GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    TIMM44
  • 別名:
    TIMM44 antibody; MIMT44 antibody; TIM44 antibody; Mitochondrial import inner membrane translocase subunit TIM44 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human TIMM44
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
  • 基因功能參考文獻:
    1. TIM44 was identified for the first time as a potential oncogene, which plays an important role in autophagy through the TIM44-SOD2-ROS-mTOR pathway. PMID: 27849558
    2. The Timm44 gene may be a new target for the treatment of type 2 diabetes PMID: 25749183
    3. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
  • 亞細胞定位:
    Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
  • 蛋白家族:
    Tim44 family
  • 數據庫鏈接:

    HGNC: 17316

    OMIM: 605058

    KEGG: hsa:10469

    STRING: 9606.ENSP00000270538

    UniGene: Hs.465784



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