在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TICAM2 Antibody

  • 中文名稱:
    TICAM2兔多克隆抗體
  • 貨號(hào):
    CSB-PA774830ESR2HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA774830ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA774830ESR2HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) TICAM2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TICAM2
  • 別名:
    Putative NF-kappa-B-activating protein 502 antibody; TCAM2_HUMAN antibody; TICAM-2 antibody; TICAM2 antibody; TIR containing adapter molecule 2 antibody; TIR domain containing adaptor protein antibody; TIR domain-containing adapter molecule 2 antibody; TIRAP 3 antibody; TIRAP3 antibody; TIRAP3a short form antibody; TIRP antibody; Toll-like receptor adaptor protein 3 antibody; Toll/interleukin-1 receptor domain-containing protein antibody; TRAM antibody; TRIF-related adapter molecule antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human TIR domain-containing adapter molecule 2 protein (1-235AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Functions as sorting adapter in different signaling pathways to facilitate downstream signaling leading to type I interferon induction. In TLR4 signaling, physically bridges TLR4 and TICAM1 and functionally transmits signal to TICAM1 in early endosomes after endocytosis of TLR4. In TLR2 signaling, physically bridges TLR2 and MYD88 and is required for the TLR2-dependent movement of MYD88 to endosomes following ligand engagement. Involved in IL-18 signaling and is proposed to function as a sorting adapter for MYD88 in IL-18 signaling during adaptive immune response. Forms a complex with RAB11FIP2 that is recruited to the phagosomes to promote the activation of the actin-regulatory GTPases RAC1 and CDC42 and subsequent phagocytosis of Gram-negative bacteria.; Proposed to inhibit LPS-TLR4 signaling at the late endosome by interaction with isoform 1 thereby disrupting the association of isoform 1 with TICAM1. May be involved in TLR4 degradation in late endosomes.
  • 亞細(xì)胞定位:
    [Isoform 1]: Cytoplasm. Golgi apparatus. Cell membrane. Endoplasmic reticulum. Early endosome membrane. Late endosome membrane. Cell projection, phagocytic cup. Note=Localized to the plasma membrane as a result of myristoylation. Phosphorylation on Ser-16 leads to its depletion from the membrane. Upon LPS stimulation colcoalizes with isoform 2 in late endosomes.; [Isoform 2]: Endoplasmic reticulum. Early endosome membrane. Late endosome membrane. Note=Translocates to late endosomes upon LPS stimulation where it colcoalizes with isoform 1.
  • 組織特異性:
    Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1).
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 21354

    OMIM: 608321

    KEGG: hsa:100302736

    STRING: 9606.ENSP00000386341

    UniGene: Hs.718838



主站蜘蛛池模板: 另类亚洲综合区图片区小说| 国产如狼似虎富婆找强壮黑人| 成在线人av无码高潮喷水| 日韩制服国产精品一区| 麻豆成人久久精品综合网址| 亚洲男人的天堂一区二区| 国产乱女乱子视频在线播放| 欧美肥妇bwbwbwbxx| 黄a无码片内射无码视频| 日日鲁鲁鲁夜夜爽爽狠狠| 欧美老妇bbbwwbbbww| 人人婷婷人人澡人人爽| 伊人久久大香线焦av综合影院| 人妻少妇精品视频二区| 奇米影视777四色狠狠| 久久精品无码一区二区app| 久久露脸国产精品| 亚洲精品99久久久久久欧美版| 色偷偷偷在线视频播放| 99国产精品人妻噜啊噜| 好了av四色综合无码久久| 亚洲乱码日产精品bd| 国产啪精品视频网站免费尤物| 国模gogo无码人体啪啪| 亚洲精品无码永久在线观看性色| 最新国产精品自在线观看| 青青青国产在线观看免费| 久久精品国产久精国产爱| 一个人看的免费高清www视频| 粉嫩av久久一区二区三区| 国产98在线 | 日韩| 中文字幕在线亚洲二区| 亚洲中文超碰中文字幕| 人人妻人人澡人人爽精品欧美 | 又大又粗又爽的少妇免费视频| 亚洲高清成人aⅴ片| 亚洲欧美在线观看品| 亚洲伊人成无码综合网| 动漫精品啪啪一区二区三区| 精品久久久久久无码人妻蜜桃| 国产日韩av一区二区三区五区|