在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TIAM2 Antibody, HRP conjugated

TIAM2 Antibody, HRP conjugated

  • 中文名稱：
    TIAM2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA818235LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TIAM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TIAM2
  • 別名：
    FLJ41865 antibody; OTTHUMP00000017472 antibody; SIF and TIAM1 like exchange factor antibody; SIF and TIAM1-like exchange factor antibody; STEF antibody; T cell lymphoma invasion and metastasis 2 antibody; T lymphoma invasion and metastasis inducing protein 2 antibody; T-lymphoma invasion and metastasis-inducing protein 2 antibody; TIAM 2 antibody; TIAM-2 antibody; Tiam2 antibody; TIAM2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 protein (1500-1627AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
  • 基因功能參考文獻：
    1. The authors show that the Rac1 selective guanine nucleotide exchange factor Sif and TIAM1-like Exchange Factor STEF, also known as TIAM2, localises to the nuclear envelope, co-localises with key perinuclear proteins and regulates the activity of perinuclear Rac1. PMID: 29844364
    2. Tiam2/Rac are key components of EphB2 trans-endocytosis and are important for cell repulsion. PMID: 27597758
    3. Results provide evidence that Sp1 positively controls TIAM2S transcription and that Sp1-mediated transcriptional activation is essential for TIAM2S ectopic expression in liver cancer cells. PMID: 26763486
    4. Knockdown of TIAM2 could up-regulate the expression of E-cadherin. PMID: 24377522
    5. TIAM2 expression was undetectable in normal human liver but was induced in all HCC cell lines and in 86% (78/91) of HCC biopsies. PMID: 21469146
    6. stef gene expressed in a stage- and region-specific manner in the mouse brain PMID: 11900975
    7. STEF protein is a guanine nucleotide exchange factor that specifically activates Rac1 in vitro and in cultured cells, which may lead to changes in the actin cytoskeletal network. PMID: 10364228

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Cell projection, neuron projection. Perikaryon.
  • 蛋白家族：
    TIAM family
  • 組織特異性：
    Expressed in the occipital, frontal and temporal lobes, cerebellum, putamen and testis.
  • 數據庫鏈接：

    HGNC: 11806

    OMIM: 604709

    KEGG: hsa:26230

    STRING: 9606.ENSP00000327315

    UniGene: Hs.586279



主站蜘蛛池模板： 在线a亚洲v天堂网2018| 最近的中文字幕在线看视频 | 国产精品久久久久高潮| 久久久久99精品成人片三人毛片 | 99re久久精品国产首页| 久久精品国产69国产精品亚洲 | 国产精品亚洲色婷婷99久久精品| 久久无码人妻一区二区三区| 人妻奶水人妻系列| 无码人妻品一区二区三区精99| 动漫av一区二区在线观看| 国产精品人妻系列21p| 国精品人妻无码一区二区三区性色| 亚洲中国精品精华液| 男人猛吃奶女人爽视频| 亚洲熟妇色自偷自拍另类| 无码国产69精品久久久久同性| 色一情一伦一区二区三| 丰满人妻被黑人中出849| av在线 亚洲 天堂| 亚洲综合另类小说色区一| 窝窝影院午夜看片| 国产偷伦视频片免费视频| 亚洲国产av无码一区二区三区| 久久99精品久久久久久蜜芽 | 精品人伦一区二区三电影| 亚洲精品久久久久久中文字幕| 精品视频一区二区三三区四区| 亚洲a综合一区二区三区| 国产啪视频1000部免费| 国产人与禽zoz0性伦多活几年| 无码av天堂一区二区三区 | 国产在线视频一区二区三区| 天天做天天爱夜夜爽| 国产粗话肉麻对白在线播放| 久久国产人妻一区二区免费| 国产成人无码精品久久久露脸| 三上悠亚人妻中文字幕在线| 看黄a大片爽爽影院免费无码| 亚洲国产成人综合在线不卡| 国产精品成人3p一区二区三区|