在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TIAL1 Antibody

TIAL1 Antibody

  • 中文名稱：
    TIAL1兔多克隆抗體
  • 貨號：
    CSB-PA023529HA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-PA023529HA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TIAL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TIAL1
  • 別名：
    Aging associated gene 7 protein antibody; Nucleolysin TIAR antibody; T cluster binding protein antibody; TCBP antibody; TIA 1 related nucleolysin antibody; TIA-1-related protein antibody; TIA1 cytotoxic granule associated RNA binding protein like 1 antibody; TIA1 related protein antibody; TIAL1 antibody; TIAR antibody; TIAR_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Nucleolysin TIAR protein (9-277AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，TIAL1 Antibody (CSB-PA023529HA01HU)，的標(biāo)記方式是Non-conjugated。對于TIAL1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA023529HB01HU TIAL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA023529HC01HU TIAL1 Antibody, FITC conjugated
    Biotin CSB-PA023529HD01HU TIAL1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    RNA-binding protein. Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.
  • 基因功能參考文獻(xiàn)：
    1. we identified MT1JP as a critical factor in restraining cell transformation by modulating p53 translation through interactions with TIAR PMID: 26909858
    2. TIAL1 inhibition of the exon 8 exclusion led to a decrease in SIRT1-Exon8 mRNA levels. PMID: 24566137
    3. A role for TIAR is identified in T-cells for control of translational specificity. PMID: 24927121
    4. findings demonstrate that TIAR recognition motif 2 (RRM2), together with its C-terminal extension, is the major contributor for the high-affinity (nM) interactions of TIAR with target RNA sequences PMID: 23603827
    5. results report the identification of TIAR as a novel player in the regulation of calcitonin/CGRP alternative RNA processing PMID: 12917321
    6. HuR, KSRP and TIAR are bound to one or more loci in the 3'UTR of IL-8 in breast cancer cells. PMID: 15514971
    7. TIAR seems to be involved in the post-transcriptional regulation of human iNOS expression PMID: 16191398
    8. Furthermore, we found that overexpression of DISC1 in SH-SY5Y cells induces the assembly of eIF3- and TIA-1-positive stress granules (SGs), discrete cytoplasmic granules formed in response to environmental stresses. PMID: 16243297
    9. TIAR-mediated inhibition of translation factor expression elicits a sustained repression of protein biosynthesis in cells responding to stress. PMID: 16537914
    10. TIAL1 maintains cytochrome c biosynthesis. PMID: 16581801
    11. adenosine/uridine (AU)-rich element-binding proteins TIA-1 (T-cell intracellular antigen-1), TIAR (TIA-1-related protein), and HuR (Hu antigen R) interact with the beta-F1-ATPase mRNA through an AU-rich sequence located to the 3'-UTR. PMID: 16890199
    12. Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. PMID: 17486099
    13. Our in vivo data, taken together with previous in vitro results, show that K-SAM splicing activation involves cooperative binding of TIA-1 and U1 snRNP to the exon's 5' splice site region. PMID: 17512901
    14. Results report the identification of a C-rich signature motif present in TIAR target mRNAs whose association with TIAR decreases following exposure to a stress-causing agent. PMID: 17682065
    15. Show increased TIA-1 positive cytotoxic T-lymphocytes in inflamed mucosa of patients with inflammatory bowel disease. PMID: 17869012
    16. In contrast with previous assumptions, the mutated residues are buried within the hydrophobic interior of the domain, where they would be likely to destabilize the RRM fold rather than directly inhibit RNA binding. PMID: 18201561

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus. Cytolytic granule. Cytoplasm, Stress granule.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11804

    OMIM: 603413

    KEGG: hsa:7073

    STRING: 9606.ENSP00000358089

    UniGene: Hs.501203



主站蜘蛛池模板： 国内精品久久久久久中文字幕| 国产成_人_综合_亚洲_国产| 日日碰狠狠添天天爽无码| 天堂√最新版中文在线地址| 亚洲和欧洲一码二码区别7777| 久久久精品456亚洲影院| 国产亚洲精品a在线观看下载| 日本大尺度吃奶呻吟视频| 亚洲国产av玩弄放荡人妇系列| 女高中生第一次破苞av| 清纯小美女主播流白浆| 欧美又大又硬又粗bbbbb| 国产高清亚洲精品视bt天堂频| 一本一道久久综合久久| 国产国拍精品av在线观看按摩| 日韩熟女精品一区二区三区 | 亚洲乱亚洲乱妇24p| 欧美性性性性o00xx| 国产高清在线精品一区免费| 亚洲日韩成人无码| 性久久久久久| 亚洲熟妇久久国产精品| 草草网站影院白丝内射| 色插图午夜影院| 欧美性xxxx狂欢老少配| 国产激情大臿免费视频| 日本韩国亚洲欧美在线| 国产成人a∨激情视频厨房| 国产成人精品a视频一区| 新区乱码无人区二精东 | 男女18禁啪啪无遮挡| 亚洲性无码av在线欣赏网| 国产福利萌白酱精品tv一区| 成年女人片免费视频播放a| 4444亚洲人成无码网在线观看 | 亚洲人成在线观看影院牛大爷| 久久人妻精品白浆国产| 国产精品久久久久久久| 无码中文字幕人妻在线一区| 超清无码波多野吉衣中文| 男人一边吃奶一边做爰免费视频|