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THRSP Antibody

  • 中文名稱:
    THRSP兔多克隆抗體
  • 貨號:
    CSB-PA846095ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: THRSPantibody at 2.13μg/ml + K562 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 17 kDa
      Observed band size: 17 kDa
    • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA846095ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA846095ESR1HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) THRSP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    THRSP
  • 別名:
    Lpgp antibody; LPGP1 antibody; MGC21659 antibody; OTTHUMP00000233866 antibody; S14 antibody; S14 protein antibody; SPOT 14 antibody; Spot 14 protein antibody; SPOT14 antibody; SPOT14 homolog antibody; Thrsp antibody; THRSP_HUMAN antibody; Thyroid hormone inducible hepatic protein antibody; Thyroid hormone responsive (SPOT14 homolog rat) antibody; Thyroid hormone responsive antibody; Thyroid hormone responsive protein antibody; Thyroid hormone responsive SPOT14 antibody; Thyroid hormone-inducible hepatic protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Thyroid hormone-inducible hepatic protein (1-146AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
  • 基因功能參考文獻:
    1. The results of the present study indicated that Spot14/S14R were differently expressed in MSC adipogenesis in AIS patients, and they may be important in the abnormal adipogenic differentiation in AIS. PMID: 27082501
    2. In human breast cancer cell lines, S14 expression was highest in those representing the luminal subtype compared to those cell lines with basal characteristics. PMID: 25472762
    3. N-terminally truncated human Thrsp and its selenomethionyl derivative were collected to 4.0, 3.0 and 3.6 A resolution PMID: 21821901
    4. significantly greater thyroid hormone response for the human promoter, compared with the rat. PMID: 12960053
    5. human Spot 14 protein might regulate the p53 target gene, p21(WAF1/Cip1), via its direct interaction with the thyroid receptor or other p53 coactivators, such as Zac1. PMID: 18299245

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  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    SPOT14 family
  • 組織特異性:
    Mainly expressed in tissues that synthesize triglycerides.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11800

    OMIM: 601926

    KEGG: hsa:7069

    STRING: 9606.ENSP00000281030

    UniGene: Hs.591969



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