在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TGM5 Antibody

  • 中文名稱:
    TGM5兔多克隆抗體
  • 貨號:
    CSB-PA913756
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,Lane 1-5: Hela cells, A431 cells, Mouse skin tissue, MCF7 cells, K562 cells,Primary antibody: CSB-PA913756(TGM5 Antibody) at dilution 1/250 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    TGM5
  • 別名:
    Protein glutamine gamma glutamyltransferase 5 antibody; Protein-glutamine gamma-glutamyltransferase 5 antibody; PSS2 antibody; TG(X) antibody; TGase 5 antibody; TGase X antibody; TGase-5 antibody; TGase5 antibody; TGASEX antibody; Tgm5 antibody; TGM5_HUMAN antibody; TGM6 antibody; TGMX antibody; TGX antibody; Transglutaminase X antibody; Transglutaminase-5 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human TGM5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
  • 基因功能參考文獻(xiàn):
    1. Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern PMID: 25510201
    2. We report both European and non-European families with acral peeling skin syndrome carrying mutations in the TGM5 gene. In 5 patients, we found 3 novel mutations: c.1001+2_1001+3del, c.1171G>A and c.1498C>T. PMID: 25644735
    3. Data trebles the number of TMG5 mutations and provides further evidence that pCly113Cys is a founder mutation in the European population. PMID: 24628291
    4. Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. PMID: 23189155
    5. TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome. PMID: 22622422
    6. analysis of a recurrent mutation in the TGM5 gene in European patients with acral peeling skin syndrome PMID: 22036214
    7. Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals. PMID: 20164844
    8. transglutaminase 5 contributes, as a secondary effect, to the hyperkeratotic phenotype in ichthyosis (both vulgaris and lamellar) and in psoriasis. PMID: 12230511
    9. Results demonstrate that transglutaminase 5 is able to induce cell death when intracellularly overexpressed. PMID: 15290346
    10. Data show that transglutaminase (TGase) 5 is acetylated at the N-terminal end, is active upon treatment with phorbol acetate, and co-localises with vimentin intermediate filaments. PMID: 15290349
    11. Transglutaminase 5 is expressed during hair follicle homeostasis. PMID: 16117804
    12. A homozygous missense mutation in TGM5 abolishes epidermal TGM5 activity and causes acral peeling skin syndrome. PMID: 16380904
    13. TG5 full-length enzyme has very low enzymatic activity, while the 53-kDa proteolytically processed form is highly active. PMID: 18509357
    14. A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family. PMID: 19440220

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Peeling skin syndrome 2 (PSS2)
  • 亞細(xì)胞定位:
    Cytoplasm. Note=Associated with intermediate filaments.
  • 蛋白家族:
    Transglutaminase superfamily, Transglutaminase family
  • 組織特異性:
    Expressed in foreskin keratinocytes.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11781

    OMIM: 603805

    KEGG: hsa:9333

    STRING: 9606.ENSP00000220420

    UniGene: Hs.129719



主站蜘蛛池模板: 亚瑟国产精品久久| av天堂永久资源网| 久久国产精品成人影院| 久久综合九色综合97网| 国产免费爽爽视频| 丝袜老师高潮呻吟高潮| 久久精品人人做人人爽97| 国产亚洲精品久久yy50| 久久久精品国产免大香伊 | 欧美性猛交xxxx免费视频软件| 亚洲精品v天堂中文字幕| 激情久久亚洲小说| 国产一本一道久久香蕉| 午夜丰满少妇性开放视频| 午夜精品国产精品大乳美女| 欧美真人性野外做爰| 中文字幕丝袜精品久久| 国产超碰人人做人人爱| 国产精品视频一区二区噜噜| 亚洲日韩乱码久久久久久| 亚洲中文字幕精品久久久久久动漫| 国产亚洲精品美女在线| 国产明星xxxx色视频| 99久久人妻无码精品系列蜜桃| 18禁美女黄网站色大片免费看| 久99久热只有精品国产女同| 中文字幕精品视频在线看免费 | 久久精品国产精品亚洲| 在线人人车操人人看视频| 97色伦综合在线欧美视频| 成人乱码一区二区三区av66| 国产精品人人妻人人爽人人牛| 最近中文字幕mv在线资源| 黑人粗大猛烈进出高潮视频| 国产69精品久久久久孕妇| 国产在线永久视频| 国精品人妻无码一区二区三区喝尿| 精品亚洲国产成人av在线时间短的| 人妻av无码系列一区二区三区 | 国产熟女亚洲精品麻豆| 99久久国产亚洲高清观看|