在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TGM5 Antibody

TGM5 Antibody

  • 中文名稱：
    TGM5兔多克隆抗體
  • 貨號：
    CSB-PA913756
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,Lane 1-5: Hela cells, A431 cells, Mouse skin tissue, MCF7 cells, K562 cells,Primary antibody: CSB-PA913756(TGM5 Antibody) at dilution 1/250 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TGM5
  • 別名：
    Protein glutamine gamma glutamyltransferase 5 antibody; Protein-glutamine gamma-glutamyltransferase 5 antibody; PSS2 antibody; TG(X) antibody; TGase 5 antibody; TGase X antibody; TGase-5 antibody; TGase5 antibody; TGASEX antibody; Tgm5 antibody; TGM5_HUMAN antibody; TGM6 antibody; TGMX antibody; TGX antibody; Transglutaminase X antibody; Transglutaminase-5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human TGM5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
  • 基因功能參考文獻(xiàn)：
    1. Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern PMID: 25510201
    2. We report both European and non-European families with acral peeling skin syndrome carrying mutations in the TGM5 gene. In 5 patients, we found 3 novel mutations: c.1001+2_1001+3del, c.1171G>A and c.1498C>T. PMID: 25644735
    3. Data trebles the number of TMG5 mutations and provides further evidence that pCly113Cys is a founder mutation in the European population. PMID: 24628291
    4. Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. PMID: 23189155
    5. TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome. PMID: 22622422
    6. analysis of a recurrent mutation in the TGM5 gene in European patients with acral peeling skin syndrome PMID: 22036214
    7. Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals. PMID: 20164844
    8. transglutaminase 5 contributes, as a secondary effect, to the hyperkeratotic phenotype in ichthyosis (both vulgaris and lamellar) and in psoriasis. PMID: 12230511
    9. Results demonstrate that transglutaminase 5 is able to induce cell death when intracellularly overexpressed. PMID: 15290346
    10. Data show that transglutaminase (TGase) 5 is acetylated at the N-terminal end, is active upon treatment with phorbol acetate, and co-localises with vimentin intermediate filaments. PMID: 15290349
    11. Transglutaminase 5 is expressed during hair follicle homeostasis. PMID: 16117804
    12. A homozygous missense mutation in TGM5 abolishes epidermal TGM5 activity and causes acral peeling skin syndrome. PMID: 16380904
    13. TG5 full-length enzyme has very low enzymatic activity, while the 53-kDa proteolytically processed form is highly active. PMID: 18509357
    14. A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family. PMID: 19440220

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Peeling skin syndrome 2 (PSS2)
  • 亞細(xì)胞定位：
    Cytoplasm. Note=Associated with intermediate filaments.
  • 蛋白家族：
    Transglutaminase superfamily, Transglutaminase family
  • 組織特異性：
    Expressed in foreskin keratinocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 11781

    OMIM: 603805

    KEGG: hsa:9333

    STRING: 9606.ENSP00000220420

    UniGene: Hs.129719



主站蜘蛛池模板： 国产成人av片无码免费| 女人被爽到高潮视频免费国产| 中国少妇内射xxxhd| 亚洲精品无码成人av电影网| 国产白嫩护士被弄高潮| 成人免费区一区二区三区| 阳茎伸入女人阳道视频免费| 永久免费的av片在线电影网| 日日婷婷夜日日天干| 天堂资源在线官网| 久久无码人妻一区二区三区午夜| 无码日韩人妻精品久久蜜桃| 成人免费视频一区二区| 永久黄网站免费视频性色| 日本高清在线www3344| 国产无遮挡又黄又爽不要vip软件| 欧美人与动牲交a精品| 色五月五月丁香亚洲综合网| 亚洲美女高清无水av| 在线不卡av片免费观看| 精品无人国产偷自产在线 | 级r片内射在线视频播放| 少妇特殊按摩高潮惨叫无码| 少女高清影视在线观看动漫| 日韩亚洲国产中文永久| 国产欧美日韩va另类在线播放| 亚洲色成人网一二三区| 国产精品高潮呻吟av久久4虎| 国产成人av激情在线播放| 在线a毛片免费视频观看| 77777_亚洲午夜久久多人| 日韩中文字幕在线一区二区三区 | 深爱婷婷国产在线精品av| 国产精品久久久久久久免费看| 玩弄japan白嫩少妇hd| 人妻夜夜爽天天爽一区| 国产人成无码视频在线1000| 色狠狠成人综合网| 国产精品久久久久久麻豆一区| 免费视频国产在线观看| 好硬好湿好爽再深一点动态图视频|