在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

TGM5 Antibody

  • 中文名稱:
    TGM5兔多克隆抗體
  • 貨號:
    CSB-PA913756
  • 規(guī)格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA913756(TGM5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,Lane 1-5: Hela cells, A431 cells, Mouse skin tissue, MCF7 cells, K562 cells,Primary antibody: CSB-PA913756(TGM5 Antibody) at dilution 1/250 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    TGM5
  • 別名:
    Protein glutamine gamma glutamyltransferase 5 antibody; Protein-glutamine gamma-glutamyltransferase 5 antibody; PSS2 antibody; TG(X) antibody; TGase 5 antibody; TGase X antibody; TGase-5 antibody; TGase5 antibody; TGASEX antibody; Tgm5 antibody; TGM5_HUMAN antibody; TGM6 antibody; TGMX antibody; TGX antibody; Transglutaminase X antibody; Transglutaminase-5 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse
  • 免疫原:
    Fusion protein of Human TGM5
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes.
  • 基因功能參考文獻(xiàn):
    1. Acral PSS (APSS) (OMIM 609796), typically non-inflammatory, is confined to distal extremities with localized exfoliation of the epidermis. It is caused by mutations in the TGM5 gene, encoding transglutaminase 5[3] or in the CTSA gene, encoding cystatin A and it is inherited in autosomal recessive pattern PMID: 25510201
    2. We report both European and non-European families with acral peeling skin syndrome carrying mutations in the TGM5 gene. In 5 patients, we found 3 novel mutations: c.1001+2_1001+3del, c.1171G>A and c.1498C>T. PMID: 25644735
    3. Data trebles the number of TMG5 mutations and provides further evidence that pCly113Cys is a founder mutation in the European population. PMID: 24628291
    4. Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis. PMID: 23189155
    5. TGM5 mutations impact epidermal differentiation in acral peeling skin syndrome. PMID: 22622422
    6. analysis of a recurrent mutation in the TGM5 gene in European patients with acral peeling skin syndrome PMID: 22036214
    7. Acral peeling skin syndrome with TGM5 gene mutations may resemble epidermolysis bullosa simplex in young individuals. PMID: 20164844
    8. transglutaminase 5 contributes, as a secondary effect, to the hyperkeratotic phenotype in ichthyosis (both vulgaris and lamellar) and in psoriasis. PMID: 12230511
    9. Results demonstrate that transglutaminase 5 is able to induce cell death when intracellularly overexpressed. PMID: 15290346
    10. Data show that transglutaminase (TGase) 5 is acetylated at the N-terminal end, is active upon treatment with phorbol acetate, and co-localises with vimentin intermediate filaments. PMID: 15290349
    11. Transglutaminase 5 is expressed during hair follicle homeostasis. PMID: 16117804
    12. A homozygous missense mutation in TGM5 abolishes epidermal TGM5 activity and causes acral peeling skin syndrome. PMID: 16380904
    13. TG5 full-length enzyme has very low enzymatic activity, while the 53-kDa proteolytically processed form is highly active. PMID: 18509357
    14. A missense mutation in TGM5 causes acral peeling skin syndrome in a Tunisian family. PMID: 19440220

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Peeling skin syndrome 2 (PSS2)
  • 亞細(xì)胞定位:
    Cytoplasm. Note=Associated with intermediate filaments.
  • 蛋白家族:
    Transglutaminase superfamily, Transglutaminase family
  • 組織特異性:
    Expressed in foreskin keratinocytes.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11781

    OMIM: 603805

    KEGG: hsa:9333

    STRING: 9606.ENSP00000220420

    UniGene: Hs.129719



主站蜘蛛池模板: 人妻插b视频一区二区三区| 国产免费无码一区二区| 在线 | 麻豆国产传媒61国产免费| 美女扒开奶罩露出奶头视频网站 | 无码人妻精品中文字幕免费东京热 | 色综合欧美五月俺也去| 一本一久本久a久久精品综合| 在线视频网站www色| 久久精品人妻一区二区三区| 亚洲熟妇av午夜无码不卡| 人妻换着玩又刺激又爽| 国产精品久久久久久亚洲色| 青青草97国产精品免费观看| 无码国内精品人妻少妇| 男女下面一进一出好爽视频| 少妇极品熟妇人妻200片| 国产精品区免费视频| 欧美激情精品久久久久久| 国产精品一区二区在线蜜芽tv| 男女免费观看在线爽爽爽视频| 中文无码av一区二区三区| 国产精品亚洲一区二区三区| 国产精品_九九99久久精品| 国产成人av 综合 亚洲| 精品人妻av一区二区三区| 欧美日韩无套内射另类| 天下第一社区视频www日本| 国产精品一区二区无线| 日本欧美大码a在线观看| 免费无码观看的av在线播放| 高潮迭起av乳颜射后入| 人妻丰满av无码久久不卡| 欧洲-级毛片内射| 首页 国产 亚洲 丝袜图片区| 把女邻居弄到潮喷的性经历| 可以看三级的网站| 在线播放人成视频观看| 色欲综合久久躁天天躁| 欧美日韩午夜群交多人轮换| 亚洲最大的imax影院| 国产亚洲日韩一区二区三区 |