在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TFB2M Antibody, Biotin conjugated

TFB2M Antibody, Biotin conjugated

  • 中文名稱：
    TFB2M兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA867154LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TFB2M Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TFB2M
  • 別名：
    N''-adenosyl(rRNA) dimethyltransferase 2 antibody; S adenosylmethionine 6 N', N' adenosyl(rRNA) dimethyltransferase 2 antibody; Dimethyladenosine transferase 2 antibody; dimethyladenosine transferase 2 mitochondrial antibody; FLJ22661 antibody; FLJ23182 antibody; h mtTFB antibody; h mtTFB2 antibody; h-mtTFB antibody; h-mtTFB2 antibody; HCV NS5A transactivated protein 5 antibody; HCV NS5A-transactivated protein 5 antibody; hepatitis C virus NS5A transactivated protein 5 antibody; Hepatitis C virus NS5A-transactivated protein 5 antibody; Hkp1 antibody; hTFB2M antibody; Mitochondrial 12S rRNA dimethylase 2 antibody; mitochondrial antibody; Mitochondrial dimethyladenosine transferase 2 antibody; Mitochondrial transcription factor B2 antibody; mtTFB antibody; mtTFB2 antibody; NS5ATP5 antibody; S-adenosylmethionine-6-N'' antibody; TFB2M antibody; TFB2M_HUMAN antibody; Transcription Factor B2 antibody; Transcription factor B2 mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Dimethyladenosine transferase 2, mitochondrial protein (30-108AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    S-adenosyl-L-methionine-dependent rRNA methyltransferase which may methylate two specific adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 12S mitochondrial rRNA (Probable). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand. Stimulates transcription independently of the methyltransferase activity.
  • 基因功能參考文獻：
    1. Study reports crystal structures of human mitochondrial transcription initiation complexes assembled on both light and heavy strand promoters. The structures reveal how transcription factors TFAM and TFB2M assist mitochondrial RNA polymerase to achieve promoter-dependent initiation. PMID: 29149603
    2. demonstrate that a complex composed of TFAM and POLRMT was readily formed at the promoter but alone was insufficient for promoter melting, which only occurred when TFB2M joined the complex PMID: 28028173
    3. The results reveal the organization of TFAM, POLRMT and TFB2M around the light-strand promoter and represent the first structural characterization of the entire mitochondrial transcriptional initiation complex. PMID: 24413562
    4. only two essential initiation factors, TFAM and TFB2M, and two promoters, LSP and HSP1, are required to drive transcription of the mitochondrial genome PMID: 20410300
    5. The mRNA levels of TFB1M and TFB2M are influenced by endurance training PMID: 19681768
    6. This transcription factor activates transcription of human mitochondrial DNA. PMID: 12068295
    7. Distinct, but possibly coordinated functions of mtTFB1 and mtTFB2 in mitochondrial gene expression and biogenesis. PMID: 17557812
    8. This study suggested that DNA variants in TFB2M did not contribute to the risk for parkinson disease. PMID: 18980857
    9. determined the variation in the TFAM, TFB1M, and TFB2M genes in cardiac hypertrophy PMID: 19096125
    10. rRNA methyltransferase activity is necessary for induction of mitochondrial biogenesis by TFB1M, but not TFB2M. PMID: 19417006
    11. Promoter-independent DNA conformation-dependent transcription required TFB2M. PMID: 19624753

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family, KsgA subfamily
  • 組織特異性：
    Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 18559

    OMIM: 607055

    KEGG: hsa:64216

    STRING: 9606.ENSP00000355471

    UniGene: Hs.7395



主站蜘蛛池模板： 无码三级中文字幕在线观看| 狠狠色丁香婷婷综合潮喷| 影音先锋人妻啪啪av资源网站 | 羞羞色男人的天堂| 伊人久久大香线蕉综合5g| 18禁免费吃奶摸下激烈视频| 中文无码乱人伦中文视频在线v| 99久久精品美女高潮喷水| 欧美婷婷丁香五月社区| 天码人妻一区二区三区| 国产熟女一区二区三区五月婷| 久久www成人_看片免费不卡| 国产丰满麻豆vⅰde0sex| 少妇激情艳情综合小视频| 欧美黑人又大又粗xxxxx| 国产精品不卡无码av在线播放 | 色欲香天天综合网站| 亚洲美女又黄又爽在线观看| 久久99精品国产麻豆婷婷| 动漫无遮挡羞视频在线观看| 性色香蕉av久久久天天网| 妺妺窝人体色www在线下载| 久久精品国产福利一区二区| 久久99精品国产99久久6| 国产ww久久久久久久久久| 黑人大荫蒂高潮视频| 国产一区二区三区精品av| 久久久久国色av免费观看| 一本精品中文字幕在线| 2018年亚洲欧美在线v| 免费午夜福利不卡片在线| 精品久久香蕉国产线看观看亚洲| 日韩精品无码视频一区二区蜜桃| 妖精色av无码国产在线看| 久久精品国自产拍| 国产欧美日韩综合精品一区二区| 国产欧美日韩综合视频专区| 熟女丝袜潮喷内裤视频网站| 久久精品国产成人av| 色偷偷av一区二区三区| 久久se精品一区二区三区|