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  4. TEX11 Antibody

TEX11 Antibody

Unavailable
  • 中文名稱：
    TEX11兔多克隆抗體
  • 貨號：
    CSB-PA023401GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TEX11
  • 別名：
    TEX11 antibody; Testis-expressed protein 11 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Human TEX11
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
  • 基因功能參考文獻：
    1. Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. PMID: 28364521
    2. Genetic screening of a large cohort of idiopathic infertile men reveals that TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of azoospermic men. PMID: 26136358
    3. TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of non-obstructive azoospermic men. PMID: 26136358
    4. hemizygous TEX11 mutations were a common cause of meiotic arrest and azoospermia in infertile men PMID: 25970010
    5. TEX11 was specifically expressed in human testis. PMID: 11279525

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  • 相關疾病：
    Spermatogenic failure, X-linked, 2 (SPGFX2)
  • 亞細胞定位：
    Chromosome.
  • 蛋白家族：
    SPO22 family
  • 組織特異性：
    Testis-specific. Not expressed in adult ovaries.
  • 數據庫鏈接：

    HGNC: 11733

    OMIM: 300311

    KEGG: hsa:56159

    STRING: 9606.ENSP00000340995

    UniGene: Hs.121776



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