在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TERT Antibody, Biotin conjugated

TERT Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    TERT兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA023391LD01DO
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Dog TERT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    TERT antibody; Telomerase reverse transcriptase antibody; EC 2.7.7.49 antibody; Telomerase catalytic subunit antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Dog
  • 免疫原：
    Recombinant Dog Telomerase reverse transcriptase protein (1-308AA)
  • 免疫原種屬：
    Dog
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
  • 基因功能參考文獻：
    1. This study evaluated the relationship between polymorphisms of Telomerase Reverse Transcriptase and the longevity and cancer susceptibility of 4 dog breeds. PMID: 24423165
    2. This study reports that the human telomerase promoter operates in canine cells, suggesting that human telomerase promoter-driven cancer therapy can be used to treat cancer in canines. PMID: 21062413
    3. Dog TERT shows the highest level of sequence similarity to the human TERT protein, supporting the dog as a model system for telomerase-based studies. PMID: 15225880
    4. Localization of catalytic subunit of telomerase reverse transcriptase in normal lens epithelial cells(LEC)corresponded with LEC's regional functions. (Catalytic subunit of telomerase reverse transcriptase) PMID: 17093391
    5. A higher expression of TERT was noted in canine and feline meningionas. PMID: 17519562
    6. These findings suggest that telomerase may be a valuable target for canine osteosarcoma (OSA) therapy, and that telomerase status does not appear to be a prognostic factor in canine OSA. PMID: 18761602
    7. DNA sequencing revealed two insertions (175 and 28 bp long) and two deletions (17 and 32 bp long), which were encountered in different combinations and gave rise to five different transcripts. PMID: 18836773
    8. TERT interacted with ERalpha via the estrogen response element (ERE) in cataractous lens epithelial cells (LEC) but not in normal LEC. PMID: 19936027

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus. Chromosome, telomere. Cytoplasm. Nucleus, PML body.
  • 蛋白家族：
    Reverse transcriptase family, Telomerase subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 真实的国产乱xxxx| 亚洲一区二区三区波多野结衣 | 欧美成 人 在线播放视频 | 国产一区二区三区影院| 亚洲精品一区久久久久久| 国产精品乱子伦xxxx| 日日躁夜夜躁狠狠躁| 女人被强╳到高潮喷水在线观看| 国产精品区一区二区三在线播放| 免费无码久久成人影片| 国产成人精品日本亚洲第一区| 免费视频爱爱太爽了网站| 国产成人精品日本亚洲| 另类老妇奶性生bbwbbw| 免费无码鲁丝片一区二区| 亚洲人成小说网站色| 青青青青国产免费线在线观看| 亚洲第一女人av| 在线а√天堂中文官网| 亚洲精品无码久久久影院相关影片 | 日本一二三区视频在线| 亚瑟国产精品久久| 色欲香天天综合网站| 成人无码视频97免费| 天天干天天日| 欧美成人精品三级网站| 中文字幕亚洲码在线观看| 国产成久久免费精品av片| 天天澡天天揉揉av在线| 国产人妻人伦精品1国产丝袜 | 国产精品va无码免费| 久久综合av色老头免费观看| 人妻影音先锋啪啪av资源| 人妻激情偷乱一区二区三区| 少妇与大狼拘作爱性a| 老熟女高潮喷水了| 久久久久人妻一区精品果冻| 欧美国产伦久久久久久久| 欧美亚洲综合成人专区| 国产97在线 | 日韩| 日韩精品成人无码专区免费|