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TCEB3 Antibody

  • 中文名稱：
    TCEB3兔多克隆抗體
  • 貨號：
    CSB-PA002320
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using Elongin A1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    ELOA
  • 別名：
    Ela1 antibody; Elo A antibody; EloA antibody; ELOA1_HUMAN antibody; Elongin 110 kDa subunit antibody; Elongin-A antibody; ElonginA antibody; RNA polymerase II transcription factor SIII subunit A1 antibody; SIII antibody; SIII p110 antibody; TCEB 3 antibody; Tceb3 antibody; TCEB3A antibody; Transcription elongation factor B (SIII) polypeptide 3 (110kD) antibody; Transcription elongation factor B (SIII) polypeptide 3 antibody; Transcription elongation factor B alpha subunit antibody; Transcription elongation factor B polypeptide 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Elongin A1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
  • 基因功能參考文獻：
    1. the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage PMID: 28292928
    2. TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors PMID: 24351681
    3. Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21. PMID: 23828199
  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    HGNC: 11620

    OMIM: 600786

    KEGG: hsa:6924

    STRING: 9606.ENSP00000395574

    UniGene: Hs.15535



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