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TCEB3 Antibody

  • 中文名稱:
    TCEB3兔多克隆抗體
  • 貨號:
    CSB-PA002320
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Jurkat cells using Elongin A1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    ELOA
  • 別名:
    Ela1 antibody; Elo A antibody; EloA antibody; ELOA1_HUMAN antibody; Elongin 110 kDa subunit antibody; Elongin-A antibody; ElonginA antibody; RNA polymerase II transcription factor SIII subunit A1 antibody; SIII antibody; SIII p110 antibody; TCEB 3 antibody; Tceb3 antibody; TCEB3A antibody; Transcription elongation factor B (SIII) polypeptide 3 (110kD) antibody; Transcription elongation factor B (SIII) polypeptide 3 antibody; Transcription elongation factor B alpha subunit antibody; Transcription elongation factor B polypeptide 3 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human Elongin A1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
  • 基因功能參考文獻:
    1. the Elongin A ubiquitin ligase and the CSB protein function together in a common pathway in response to Pol II stalling and DNA damage PMID: 28292928
    2. TCEB3C is a putative tumor suppressor gene of small intestinal neuroendocrine tumors PMID: 24351681
    3. Elongin A transcription elongation activity, but not its ubiquitination activity, is most important for its function in induction of transcription of ATF3 and p21. PMID: 23828199
  • 亞細胞定位:
    Nucleus.
  • 數據庫鏈接:

    HGNC: 11620

    OMIM: 600786

    KEGG: hsa:6924

    STRING: 9606.ENSP00000395574

    UniGene: Hs.15535



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