在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. TBX22 Antibody

TBX22 Antibody

  • 中文名稱：
    TBX22兔多克隆抗體
  • 貨號：
    CSB-PA023253GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    TBX22
  • 別名：
    TBX22 antibody; TBOX22 antibody; T-box transcription factor TBX22 antibody; T-box protein 22 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TBX22
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.
  • 基因功能參考文獻：
    1. Findings indicate the important role of T-box 22 protein (TBX22) in familial cases with X-linked cleft palate. PMID: 29932061
    2. we analysed two TBX22 promoter rs7055763 and rs41307258 single-nucleotide polymorphisms (SNPs) in 173 patients with NSCLP and 176 normal controls of south Indian origin using Kbioscience KASPar chemistry PMID: 25918826
    3. These results suggest that a loss-of-function mutation in the X-linked TBX22 promoter may cause the cleft palate through disruption of TBX22-ETS-1 pathway. PMID: 25373698
    4. TBX22 is the gene underlying Abruzzo-Erickson syndrome. PMID: 22784330
    5. 5 putative missense mutations were identified, 3 located in T-box binding domain (R120Q, R126W, and R151L) that affects DNA binding and/or transcriptional repression. 2 novel C-terminal mutations, P389Q and S400Y, did not affect TBX22 activity. PMID: 21248356
    6. Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia (CPX) phenotype observed in CPX patients. PMID: 12374769
    7. Four novel TBX22 splice site mutations in North American and Brazilian cleft palate families. PMID: 14729838
    8. TBX22 is a target for the small ubiquitin-like modifier SUMO-1 and this modification is required for TBX22 repressor activity. PMID: 17846996
    9. TBX22 mutations are responsible for a significant proportion of Thai non-syndromic cleft palate cases. PMID: 17868388
    10. Analysis of the TBX22 promoter region revealed seven sequence variants, two of which are associated with cleft palate; this effect is stronger in a subgroup stratified for the presence of ankyloglossia. PMID: 19648124

    顯示更多

    收起更多

  • 相關疾病：
    Cleft palate with or without ankyloglossia, X-linked (CPX); Abruzzo-Erickson syndrome (ABERS)
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Seems to be expressed at a low level.
  • 數據庫鏈接：

    HGNC: 11600

    OMIM: 300307

    KEGG: hsa:50945

    STRING: 9606.ENSP00000362390

    UniGene: Hs.374253



主站蜘蛛池模板： 国产在线欧美日韩精品一区| 国产亚洲精品久久久久久牛牛| 最新在线精品国产福利| 欧美国产日韩a在线视频下载| 欧美精品videosex极品| 亚洲国产天堂久久综合| 成人电线在线播放无码| 亚洲天天做日日做天天欢毛片| 亚洲无线卡一卡二| 69sex久久精品国产麻豆| 精品久久久久久无码专区| 亚洲成本人无码薄码区| 国产av一区二区精品久久| 又粗又硬又大又爽免费视频播放| 无码人妻精品一区二| 国产精品毛片在线完整版| 亚洲日韩亚洲另类| 成人无码一区二区三区| 久久综合一色综合久久小蛇| 人妻出差精油按摩被中出| 粉嫩大学生无套内射无码卡视频| 中国产xxxxa片在线观看| 无码精品国产一区二区三区免费| 国产综合视频一区二区三区| 少妇无码av无码专区| 18禁裸体女免费观看| 久久影院九九被窝爽爽| 免费人成网视频在线观看 | 偷偷要色偷偷中文无码| 亚洲精品tv久久久久久久久j| 国产精品久久久久久久久久免费| 小蜜被两老头吸奶头在线观看| 中文字幕亚洲精品乱码| 18禁成年无码免费网站| 男女性色大片免费网站| 欧美网站免费观看在线| 久久理论片午夜琪琪电影网| 曰本无码人妻丰满熟妇啪啪| 少妇与黑人一二三区无码| 黑人又粗又大又硬a片| 欧美午夜刺激影院|