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TBC1D7 Antibody, HRP conjugated

  • 中文名稱:
    TBC1D7兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA873720LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) TBC1D7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    TBC1D7
  • 別名:
    TBC1D7 antibody; TBC7 antibody; HSPC239 antibody; TBC1 domain family member 7 antibody; Cell migration-inducing protein 23 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human TBC1 domain family member 7 protein (1-293AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
  • 相關疾病:
    Macrocephaly/megalencephaly syndrome, autosomal recessive (MGCPH)
  • 亞細胞定位:
    Cytoplasmic vesicle. Note=Localizes in the cytoplasmic vesicles of the endomembrane in association with TSC1-TSC2 complex.
  • 組織特異性:
    Highly expressed in heart, and slightly in kidney, liver and placenta.
  • 數據庫鏈接:

    HGNC: 21066

    OMIM: 248000

    KEGG: hsa:107080638

    STRING: 9606.ENSP00000348813

    UniGene: Hs.484678



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