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TBC1D14 Antibody

  • 中文名稱：
    TBC1D14兔多克隆抗體
  • 貨號：
    CSB-PA889187LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: TBC1D14 antibody at 4μg/ml
      Lane 1: K562 whole cell lysate
      Lane 2: U87 whole cell lysate
      Lane 3: A549 whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 79, 48 kDa
      Observed band size: 79 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA889187LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA889187LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TBC1D14 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TBC1D14
  • 別名：
    FLJ32400 antibody; KIAA1322 antibody; TBC1 domain family member 14 antibody; TBC14_HUMAN antibody; Tbc1d14 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human TBC1 domain family member 14 protein (136-435AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，TBC1D14 Antibody (CSB-PA889187LA01HU)，的標記方式是Non-conjugated。對于TBC1D14 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA889187LB01HU TBC1D14 Antibody, HRP conjugated ELISA
    FITC CSB-PA889187LC01HU TBC1D14 Antibody, FITC conjugated
    Biotin CSB-PA889187LD01HU TBC1D14 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in the regulation of starvation-induced autophagosome formation. Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy.
  • 基因功能參考文獻：
    1. TRAPPC8 modulates autophagy and secretory trafficking and is required for TBC1D14 to bind TRAPPIII. PMID: 26711178
    2. TBC1D14 binds activated Rab11 but is not a GAP for Rab11, and loss of Rab11 prevents TBC1D14-induced tubulation of recycling endosomes. PMID: 22613832
    3. crystal structures of the first two mammalian TBCs, human TBC1 family members 22A (TBC1D22A) and 14 (TBC1D14) PMID: 18186464
  • 亞細胞定位：
    Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network. Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation.
  • 數據庫鏈接：

    HGNC: 29246

    OMIM: 614855

    KEGG: hsa:57533

    STRING: 9606.ENSP00000386921

    UniGene: Hs.518611



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