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  4. TAF2 Antibody, HRP conjugated

TAF2 Antibody, HRP conjugated

  • 中文名稱：
    TAF2兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA747395LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) TAF2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TAF2
  • 別名：
    TAF2 antibody; CIF150 antibody; TAF2B antibody; Transcription initiation factor TFIID subunit 2 antibody; 150 kDa cofactor of initiator function antibody; RNA polymerase II TBP-associated factor subunit B antibody; TBP-associated factor 150 kDa antibody; Transcription initiation factor TFIID 150 kDa subunit antibody; TAF(II)150 antibody; TAFII-150 antibody; TAFII150 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription initiation factor TFIID subunit 2 protein (400-450AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. It requires core promoter-specific cofactors for productive transcription stimulation. TAF2 stabilizes TFIID binding to core promoter.
  • 基因功能參考文獻：
    1. the TAF2-TAF8-TAF10 complex demonstrates that there is a stepwise assembly pathway of nuclear holo-TFIID, regulated by nuclear import of preformed cytoplasmic submodules PMID: 25586196
    2. This study suggested that the Microcephaly thin corpus callosum intellectual disability syndrome is caused by the more conserved mutation p.Thr186Arg, with the second sequence change identified, p.Pro416His. PMID: 24084144
  • 相關疾病：
    Mental retardation, autosomal recessive 40 (MRT40)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TAF2 family
  • 組織特異性：
    Expressed in all tissues tested.
  • 數據庫鏈接：

    HGNC: 11536

    OMIM: 604912

    KEGG: hsa:6873

    STRING: 9606.ENSP00000367406

    UniGene: Hs.122752



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